High frequency of toxigenic Clostridium difficile and Clostridium perfringens coinfection among diarrheic patients at health care facility-onset (HCFO) and community-onset (CO) centers in Bogotá, Colombia

Alex J. Forero, Marina Muñoz, Milena Camargo, Sara C. Soto-De León, Dora I. Ríos-Chaparro, Claudia Birchenall, Darío Pinilla, Juan Mauricio Pardo Oviedo, Diego F. Josa, Manuel A. Patarroyo, Juan D. Ramírez

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

4 Citas (Scopus)

Resumen

Background: The aim of this study was to evaluate the frequency of toxigenic C. difficile and C. perfringens infections at health care facility-onset (HCFO) and community-onset (CO), in two health care centers (HCC) in Bogotá, Colombia. A total of 220 stool samples from patients presenting diarrhea acquired at HCFO or CO were analyzed by several PCR tests. Results: We found that 65.5% (n = 144) of the population had C. difficile infection, followed by toxigenic C. difficile with 57.3% (n = 126), and finally toxigenic C. perfringens with a frequency of 32.7% (n = 72). Conclusions: This study is the first molecular detection and characterization of C. difficile and C. perfringens in HCFO and CO in Latin America and demonstrates a relevant frequency of these two species, including coinfection and strikingly diverse toxigenic profiles, especially in the CO.

Idioma originalInglés estadounidense
Número de artículo27
PublicaciónGut Pathogens
Volumen11
N.º1
DOI
EstadoPublicada - jun. 3 2019

Áreas temáticas de ASJC Scopus

  • Parasitología
  • Microbiología
  • Gastroenterología
  • Virología
  • Enfermedades infecciosas

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Profundice en los temas de investigación de 'High frequency of toxigenic Clostridium difficile and Clostridium perfringens coinfection among diarrheic patients at health care facility-onset (HCFO) and community-onset (CO) centers in Bogotá, Colombia'. En conjunto forman una huella única.

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