Resumen
| Idioma original | English (US) |
|---|---|
| Páginas (desde-hasta) | 72-81 |
| Número de páginas | 10 |
| Publicación | Immunologic Research |
| Volumen | 65 |
| N.º | 1 |
| Estado | Published - 2016 |
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Guillain-Barré syndrome in Colombia: where do we stand now? / Anaya, Juan-Manuel; Sarmiento-Monroy, Juan Camilo; Ojeda, Ernesto; Vega, Daniel A.
En: Immunologic Research, Vol. 65, N.º 1, 2016, p. 72-81.Resultado de la investigación: Contribución a Revista › Artículo
TY - JOUR
T1 - Guillain-Barré syndrome in Colombia: where do we stand now?
AU - Anaya, Juan-Manuel
AU - Sarmiento-Monroy, Juan Camilo
AU - Ojeda, Ernesto
AU - Vega, Daniel A.
PY - 2016
Y1 - 2016
N2 - Guillain-Barré syndrome (GBS) is a rapid-onset muscle weakness disease caused by the immune-mediated damage of the peripheral nervous system. Since there is an increase incidence of GBS cases in Latin America, particularly in Colombia, and most of them are currently preceded by Zika virus (ZIKV) infection, we aimed to assess the available evidence of the disease in Colombia through a systematic literature review. Out of 51 screened abstracts, only 16 corresponded to articles that met inclusion criteria, of which 15 were case reports or case series. A total of 796 cases of GBS were reported in the included articles. The majority of patients were males (66.8 %) and younger than 50 years old (94 %). An infectious disease before the onset of GBS was registered in 31 % of patients, with gastrointestinal or respiratory symptoms being the most frequently observed. In those cases in which electrodiagnostic tests were performed, the most common subphenotype was acute inflammatory demyelinating polyneuropathy (17 %). Death was reported in 15 % of patients. Data regarding GBS in Colombia is scant and heterogeneous. Taking into account the burden of the disease and the recent rise of GBS cases associated with ZIKV, a careful patient evaluation and a systematic collection of data are warranted. A form to data gathering is proposed.
AB - Guillain-Barré syndrome (GBS) is a rapid-onset muscle weakness disease caused by the immune-mediated damage of the peripheral nervous system. Since there is an increase incidence of GBS cases in Latin America, particularly in Colombia, and most of them are currently preceded by Zika virus (ZIKV) infection, we aimed to assess the available evidence of the disease in Colombia through a systematic literature review. Out of 51 screened abstracts, only 16 corresponded to articles that met inclusion criteria, of which 15 were case reports or case series. A total of 796 cases of GBS were reported in the included articles. The majority of patients were males (66.8 %) and younger than 50 years old (94 %). An infectious disease before the onset of GBS was registered in 31 % of patients, with gastrointestinal or respiratory symptoms being the most frequently observed. In those cases in which electrodiagnostic tests were performed, the most common subphenotype was acute inflammatory demyelinating polyneuropathy (17 %). Death was reported in 15 % of patients. Data regarding GBS in Colombia is scant and heterogeneous. Taking into account the burden of the disease and the recent rise of GBS cases associated with ZIKV, a careful patient evaluation and a systematic collection of data are warranted. A form to data gathering is proposed.
UR - https://www.ncbi.nlm.nih.gov/pubmed/27421717
M3 - Article
VL - 65
SP - 72
EP - 81
JO - Immunologic Research
JF - Immunologic Research
SN - 0257-277X
IS - 1
ER -