Genetics and Vaccinology

John Castiblanco, Juan-Manuel Anaya

Resultado de la investigación: Contribución a libro /Tipo informe o reporteCapítulo

Resumen

Vaccines are the most effective and sustainable means of preventing infectious diseases. Novel diagnostics would help customize the use of vaccines in subpopulations in which they would display enhanced safety and efficacy. This chapter focuses on giving a glimpse of the genetic status effect of vaccine immune response and how this could contribute to the development of novel vaccine candidates that are better directed and predicted relative to the genetic history of an individual and/or population. It provides a summary of genetic factors associated with human leukocyte antigen (HLA) alleles and single nucleotide polymorphisms (SNPs) in multiple classes of genes that provide immune response to vaccines. The immune response network theory, in its simplest form, is based on the premise “the response to a vaccine is the cumulative result of interactions driven by a host of genes and their interactions, and is theoretically predictable”.
Idioma originalEnglish (US)
Título de la publicación alojadaVaccines and Autoimmunity
Páginas65-78
Número de páginas14
DOI
EstadoPublished - 2015

Serie de la publicación

NombreVaccines and Autoimmunity

Huella dactilar

Vaccines
HLA Antigens
Genes
Single Nucleotide Polymorphism
Communicable Diseases
History
Alleles
Safety
Population

Citar esto

Castiblanco, J., & Anaya, J-M. (2015). Genetics and Vaccinology. En Vaccines and Autoimmunity (pp. 65-78). (Vaccines and Autoimmunity). https://doi.org/10.1002/9781118663721.ch6
Castiblanco, John ; Anaya, Juan-Manuel. / Genetics and Vaccinology. Vaccines and Autoimmunity. 2015. pp. 65-78 (Vaccines and Autoimmunity).
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Castiblanco, J & Anaya, J-M 2015, Genetics and Vaccinology. En Vaccines and Autoimmunity. Vaccines and Autoimmunity, pp. 65-78. https://doi.org/10.1002/9781118663721.ch6

Genetics and Vaccinology. / Castiblanco, John; Anaya, Juan-Manuel.

Vaccines and Autoimmunity. 2015. p. 65-78 (Vaccines and Autoimmunity).

Resultado de la investigación: Contribución a libro /Tipo informe o reporteCapítulo

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Castiblanco J, Anaya J-M. Genetics and Vaccinology. En Vaccines and Autoimmunity. 2015. p. 65-78. (Vaccines and Autoimmunity). https://doi.org/10.1002/9781118663721.ch6