Gender differences in latin-american patients with rheumatoid arthritis

Carolina Barragán-Martínez, Jenny Amaya-Amaya, Ricardo Pineda-Tamayo, Rubén D. Mantilla, Juan Castellanos-De La Hoz, Santiago Bernal-Macías, Adriana Rojas-Villarraga, Juan Manuel Anaya

Resultado de la investigación: Contribución a RevistaArtículo

18 Citas (Scopus)

Resumen

Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. © 2012 Elsevier HS Journals, Inc.
Idioma originalEnglish (US)
Páginas (desde-hasta)490-510
Número de páginas21
PublicaciónGender Medicine
DOI
EstadoPublished - dic 1 2012

Huella dactilar

Latin America
gender-specific factors
gender
disability

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Barragán-Martínez, C., Amaya-Amaya, J., Pineda-Tamayo, R., Mantilla, R. D., Castellanos-De La Hoz, J., Bernal-Macías, S., ... Anaya, J. M. (2012). Gender differences in latin-american patients with rheumatoid arthritis. Gender Medicine, 490-510. https://doi.org/10.1016/j.genm.2012.10.005
Barragán-Martínez, Carolina ; Amaya-Amaya, Jenny ; Pineda-Tamayo, Ricardo ; Mantilla, Rubén D. ; Castellanos-De La Hoz, Juan ; Bernal-Macías, Santiago ; Rojas-Villarraga, Adriana ; Anaya, Juan Manuel. / Gender differences in latin-american patients with rheumatoid arthritis. En: Gender Medicine. 2012 ; pp. 490-510.
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abstract = "Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. {\circledC} 2012 Elsevier HS Journals, Inc.",
author = "Carolina Barrag{\'a}n-Mart{\'i}nez and Jenny Amaya-Amaya and Ricardo Pineda-Tamayo and Mantilla, {Rub{\'e}n D.} and {Castellanos-De La Hoz}, Juan and Santiago Bernal-Mac{\'i}as and Adriana Rojas-Villarraga and Anaya, {Juan Manuel}",
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Barragán-Martínez, C, Amaya-Amaya, J, Pineda-Tamayo, R, Mantilla, RD, Castellanos-De La Hoz, J, Bernal-Macías, S, Rojas-Villarraga, A & Anaya, JM 2012, 'Gender differences in latin-american patients with rheumatoid arthritis', Gender Medicine, pp. 490-510. https://doi.org/10.1016/j.genm.2012.10.005

Gender differences in latin-american patients with rheumatoid arthritis. / Barragán-Martínez, Carolina; Amaya-Amaya, Jenny; Pineda-Tamayo, Ricardo; Mantilla, Rubén D.; Castellanos-De La Hoz, Juan; Bernal-Macías, Santiago; Rojas-Villarraga, Adriana; Anaya, Juan Manuel.

En: Gender Medicine, 01.12.2012, p. 490-510.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Gender differences in latin-american patients with rheumatoid arthritis

AU - Barragán-Martínez, Carolina

AU - Amaya-Amaya, Jenny

AU - Pineda-Tamayo, Ricardo

AU - Mantilla, Rubén D.

AU - Castellanos-De La Hoz, Juan

AU - Bernal-Macías, Santiago

AU - Rojas-Villarraga, Adriana

AU - Anaya, Juan Manuel

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. © 2012 Elsevier HS Journals, Inc.

AB - Background: Data on the effect of gender in rheumatoid arthritis (RA) in non-Caucasian populations is scarce. Latin America and the Caribbean (LAC) is a large population with unique characteristics, including high admixture. Objective: Our aim was to examine the effect of gender in patients with RA in LAC. Methods: This was a 2-phase study. First we conducted a cross-sectional and analytical study in which 1128 consecutive Colombian patients with RA were assessed. Second, a systematic review of the literature was done to evaluate the effect of gender in LAC patients with RA. Results: Our results show a high prevalence of RA in LAC women with a ratio of 5.2 women per man. Colombian women with RA are more at risk of having an early age at onset and developing polyautoimmunity and abdominal obesity, and they perform more household duties than their male counterparts. However, male gender was associated with the presence of extra-articular manifestations. Of a total of 641 potentially relevant articles, 38 were considered for final analysis, in which several factors and outcomes related to gender were identified. Conclusions: RA in LAC women is not only more common but presents with some clinical characteristics that differ from RA presentation in men. Some of those characteristics could explain the high rates of disability and worse prognosis observed in women with RA in LAC. © 2012 Elsevier HS Journals, Inc.

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DO - 10.1016/j.genm.2012.10.005

M3 - Article

C2 - 23217568

SP - 490

EP - 510

JO - Gender Medicine

JF - Gender Medicine

SN - 1550-8579

ER -

Barragán-Martínez C, Amaya-Amaya J, Pineda-Tamayo R, Mantilla RD, Castellanos-De La Hoz J, Bernal-Macías S y otros. Gender differences in latin-american patients with rheumatoid arthritis. Gender Medicine. 2012 dic 1;490-510. https://doi.org/10.1016/j.genm.2012.10.005