Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

Juan F Cano; Julián Ortegón-Valencia; Carlos Pedraza-Perez; Rodrigo Córdoba-Rojas; Ana Olarte-Armenta; Alexie Vallejo-Silva; Jairo González-Díaz

doi:10.1016/j.rcp.2020.11.005

Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

Título traducido de la contribución: Funcionalidad en los primeros cinco años después del diagnóstico de esquizofrenia. Estudio de cohorte en población colombiana

Juan F Cano
, Julián Ortegón-Valencia
, Carlos Pedraza-Perez
, Rodrigo Córdoba-Rojas
, Ana Olarte-Armenta
, Alexie Vallejo-Silva
, Jairo González-Díaz

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

Resumen

Objetivo
Existe una falta de estudios en la historia natural de los estadios iniciales de la esquizofrenia en Colombia. Este estudio apunta a evaluar la funcionalidad en los primeros cinco años después del diagnóstico de esquizofrenia.

Método
Estudio longitudinal naturalístico de 50 pacientes con esquizofrenia temprana evaluados entre los años 2011 y 2014. Loa datos demográficos, síntomas, introspección, tratamiento, y reacciones adversas fueron recolectados en todos los pacientes cada 3 meses por lo menos 3 a 5 años. La funcionalidad se midió mediante la escala global de funcionamiento (GAF), y la escala de funcionamiento personal y social (PSP).

Resultados
Los pacientes fueron seguidos por una media de 174 semanas (SD: 62.5) y mostraron dificultades moderadas en su funcionamiento global. Este funcionamiento fue modificado por la presencia de polifarmacia, grado de introspección, cambios en los esquemas antipsicóticos, y el número de episodios, recaídas, y hospitalizaciones.

Conclusiones
Los resultados sugieren que los desenlaces en funcionalidad parecen estar relacionados con uso de polifarmacia, grado de introspección, cambios en esquemas antipsicóticos, y numero de episodios, recaídas, y hospitalizaciones durante los primeros años de esquizofrenia.

Título traducido de la contribución	Funcionalidad en los primeros cinco años después del diagnóstico de esquizofrenia. Estudio de cohorte en población colombiana
Idioma original	Inglés estadounidense
Páginas (desde-hasta)	183-191
Número de páginas	9
Publicación	Revista Colombiana de Psiquiatria
Volumen	51
N.º	3
DOI	https://doi.org/10.1016/j.rcp.2020.11.005
Estado	Publicada - ago. 2022

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar

Áreas temáticas de ASJC Scopus

Psiquiatría y salud mental

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10.1016/j.rcp.2020.11.005

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@article{2f2c7402ab3c454f8c2df5467f0578be,

title = "Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population",

abstract = "ObjectiveThere is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. MethodsNaturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. ResultsPatients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. ConclusionsThe results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.",

author = "Cano, \{Juan F\} and Juli{\'a}n Orteg{\'o}n-Valencia and Carlos Pedraza-Perez and Rodrigo C{\'o}rdoba-Rojas and Ana Olarte-Armenta and Alexie Vallejo-Silva and Jairo Gonz{\'a}lez-D{\'i}az",

year = "2022",

month = aug,

doi = "10.1016/j.rcp.2020.11.005",

language = "English (US)",

volume = "51",

pages = "183--191",

journal = "Revista Colombiana de Psiquiatria",

issn = "0034-7450",

publisher = "Asociacion Colombiana de Psiquiatria",

number = "3",

}

Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population. / Cano, Juan F; Ortegón-Valencia, Julián; Pedraza-Perez, Carlos et al.
En: Revista Colombiana de Psiquiatria, Vol. 51, N.º 3, 08.2022, p. 183-191.

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

TY - JOUR

T1 - Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

AU - Cano, Juan F

AU - Ortegón-Valencia, Julián

AU - Pedraza-Perez, Carlos

AU - Córdoba-Rojas, Rodrigo

AU - Olarte-Armenta, Ana

AU - Vallejo-Silva, Alexie

AU - González-Díaz, Jairo

PY - 2022/8

Y1 - 2022/8

N2 - ObjectiveThere is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. MethodsNaturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. ResultsPatients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. ConclusionsThe results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.

AB - ObjectiveThere is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. MethodsNaturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. ResultsPatients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. ConclusionsThe results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.

UR - https://www.scopus.com/pages/publications/85098871936

U2 - 10.1016/j.rcp.2020.11.005

DO - 10.1016/j.rcp.2020.11.005

M3 - Research Article

C2 - 33735038

AN - SCOPUS:85098871936

SN - 0034-7450

VL - 51

SP - 183

EP - 191

JO - Revista Colombiana de Psiquiatria

JF - Revista Colombiana de Psiquiatria

IS - 3

ER -

Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

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ODS de las Naciones Unidas

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