Frequency of Human Papillomavirus Infection, Coinfection, and Association with Different Risk Factors in Colombia

Milena Camargo, Sara C. Soto-De Leon, Ricardo Sanchez, Antonio Perez-Prados, Manuel E. Patarroyo, Manuel A. Patarroyo

Resultado de la investigación: Contribución a RevistaArtículo

17 Citas (Scopus)

Resumen

Purpose: The aims of this study were to provide new insights into infection patterns of six high-risk human papillomaviruses (HR-HPV-16, -18, -31, -33, -45, and -58) and two low-risk HPV types (LR-HPV-6 and -11), their association with risk factors and coinfection. Methods: Cervical samples of 2110 women were tested for the presence of HPV-DNA by polymerase chain reaction. Statistical analyses were performed to determine viral-type frequencies in single and multiple infections and association between infection and different risk factors. Results: HPV-16 was the most prevalent type among the studied population, followed by HPV-31. This last viral type showed a variable distribution between the different cities evaluated. The results showed distinct type-specific distributions among regions and a high association between absence of pregnancies, cities as Girardot and Leticia, the indigenous ethnicity, and coinfection. Conclusions: The results showed a variable distribution of HPV types according to the geographical region analyzed. In addition, data suggest that some sociodemographic-factors such as ethnicity, number of pregnancies, lifetime number of sexual partners, and geographic region were significantly associated, and our results showed little differences between single and multiple infections by HPV with regard to risk factors. Furthermore, these results provide relevant information that will allow assessing in further studies the impact that vaccination programs on these populations and the selective pressure would have on the distribution of HPV types. © 2011 Elsevier Inc.
Idioma originalEnglish (US)
Páginas (desde-hasta)204-213
Número de páginas10
PublicaciónAnnals of Epidemiology
DOI
EstadoPublished - mar 1 2011

Huella dactilar

Papillomavirus Infections
Colombia
Coinfection
Human papillomavirus 16
Infection
Human papillomavirus 31
Human papillomavirus 11
Human papillomavirus 6
Human papillomavirus 18
Pregnancy
Sexual Partners
Population Dynamics
DNA-Directed DNA Polymerase
Vaccination
Polymerase Chain Reaction
Population

Citar esto

Camargo, Milena ; Soto-De Leon, Sara C. ; Sanchez, Ricardo ; Perez-Prados, Antonio ; Patarroyo, Manuel E. ; Patarroyo, Manuel A. / Frequency of Human Papillomavirus Infection, Coinfection, and Association with Different Risk Factors in Colombia. En: Annals of Epidemiology. 2011 ; pp. 204-213.
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abstract = "Purpose: The aims of this study were to provide new insights into infection patterns of six high-risk human papillomaviruses (HR-HPV-16, -18, -31, -33, -45, and -58) and two low-risk HPV types (LR-HPV-6 and -11), their association with risk factors and coinfection. Methods: Cervical samples of 2110 women were tested for the presence of HPV-DNA by polymerase chain reaction. Statistical analyses were performed to determine viral-type frequencies in single and multiple infections and association between infection and different risk factors. Results: HPV-16 was the most prevalent type among the studied population, followed by HPV-31. This last viral type showed a variable distribution between the different cities evaluated. The results showed distinct type-specific distributions among regions and a high association between absence of pregnancies, cities as Girardot and Leticia, the indigenous ethnicity, and coinfection. Conclusions: The results showed a variable distribution of HPV types according to the geographical region analyzed. In addition, data suggest that some sociodemographic-factors such as ethnicity, number of pregnancies, lifetime number of sexual partners, and geographic region were significantly associated, and our results showed little differences between single and multiple infections by HPV with regard to risk factors. Furthermore, these results provide relevant information that will allow assessing in further studies the impact that vaccination programs on these populations and the selective pressure would have on the distribution of HPV types. {\circledC} 2011 Elsevier Inc.",
author = "Milena Camargo and {Soto-De Leon}, {Sara C.} and Ricardo Sanchez and Antonio Perez-Prados and Patarroyo, {Manuel E.} and Patarroyo, {Manuel A.}",
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Frequency of Human Papillomavirus Infection, Coinfection, and Association with Different Risk Factors in Colombia. / Camargo, Milena; Soto-De Leon, Sara C.; Sanchez, Ricardo; Perez-Prados, Antonio; Patarroyo, Manuel E.; Patarroyo, Manuel A.

En: Annals of Epidemiology, 01.03.2011, p. 204-213.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Frequency of Human Papillomavirus Infection, Coinfection, and Association with Different Risk Factors in Colombia

AU - Camargo, Milena

AU - Soto-De Leon, Sara C.

AU - Sanchez, Ricardo

AU - Perez-Prados, Antonio

AU - Patarroyo, Manuel E.

AU - Patarroyo, Manuel A.

PY - 2011/3/1

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AB - Purpose: The aims of this study were to provide new insights into infection patterns of six high-risk human papillomaviruses (HR-HPV-16, -18, -31, -33, -45, and -58) and two low-risk HPV types (LR-HPV-6 and -11), their association with risk factors and coinfection. Methods: Cervical samples of 2110 women were tested for the presence of HPV-DNA by polymerase chain reaction. Statistical analyses were performed to determine viral-type frequencies in single and multiple infections and association between infection and different risk factors. Results: HPV-16 was the most prevalent type among the studied population, followed by HPV-31. This last viral type showed a variable distribution between the different cities evaluated. The results showed distinct type-specific distributions among regions and a high association between absence of pregnancies, cities as Girardot and Leticia, the indigenous ethnicity, and coinfection. Conclusions: The results showed a variable distribution of HPV types according to the geographical region analyzed. In addition, data suggest that some sociodemographic-factors such as ethnicity, number of pregnancies, lifetime number of sexual partners, and geographic region were significantly associated, and our results showed little differences between single and multiple infections by HPV with regard to risk factors. Furthermore, these results provide relevant information that will allow assessing in further studies the impact that vaccination programs on these populations and the selective pressure would have on the distribution of HPV types. © 2011 Elsevier Inc.

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