Fatal disseminated cryptococcus gattii infection in New Mexico

Carla J. Walraven; Wendy Gerstein; Sarah E. Hardison; Floyd Wormley; Shawn R. Lockhart; Julie R. Harris; Annette Fothergill; Brian Wickes; Julie Gober-Wilcox; Larry Massie; T. S.Neil Ku; Carolina Firacative; Wieland Meyer; Samuel A. Lee

doi:10.1371/journal.pone.0028625

Fatal disseminated cryptococcus gattii infection in New Mexico

Carla J. Walraven
, Wendy Gerstein
, Sarah E. Hardison
, Floyd Wormley
, Shawn R. Lockhart
, Julie R. Harris
, Annette Fothergill
, Brian Wickes
, Julie Gober-Wilcox
, Larry Massie
, T. S.Neil Ku
, Carolina Firacative
, Wieland Meyer
, Samuel A. Lee

Producción científica: Contribución a revista › Artículo de Investigación › revisión exhaustiva

36 Citas (Scopus)

Resumen

We report a case of fatal disseminated infection with Cryptococcus gattii in a patient from New Mexico. The patient had no history of recent travel to known C. gattii-endemic areas. Multilocus sequence typing revealed that the isolate belonged to the major molecular type VGIII. Virulence studies in a mouse pulmonary model of infection demonstrated that the strain was less virulent than other C. gattii strains. This represents the first documented case of C. gattii likely acquired in New Mexico.

Idioma original	Inglés estadounidense
Número de artículo	e28625
Publicación	PLOS ONE
Volumen	6
N.º	12
DOI	https://doi.org/10.1371/journal.pone.0028625
Estado	Publicada - dic 14 2011
Publicado de forma externa	Sí

Áreas temáticas de ASJC Scopus

Bioquímica, Genética y Biología Molecular General
Ciencias Agrícolas y Biológicas General
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title = "Fatal disseminated cryptococcus gattii infection in New Mexico",

abstract = "We report a case of fatal disseminated infection with Cryptococcus gattii in a patient from New Mexico. The patient had no history of recent travel to known C. gattii-endemic areas. Multilocus sequence typing revealed that the isolate belonged to the major molecular type VGIII. Virulence studies in a mouse pulmonary model of infection demonstrated that the strain was less virulent than other C. gattii strains. This represents the first documented case of C. gattii likely acquired in New Mexico.",

author = "Walraven, \{Carla J.\} and Wendy Gerstein and Hardison, \{Sarah E.\} and Floyd Wormley and Lockhart, \{Shawn R.\} and Harris, \{Julie R.\} and Annette Fothergill and Brian Wickes and Julie Gober-Wilcox and Larry Massie and Ku, \{T. S.Neil\} and Carolina Firacative and Wieland Meyer and Lee, \{Samuel A.\}",

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AU - Walraven, Carla J.

AU - Gerstein, Wendy

AU - Hardison, Sarah E.

AU - Wormley, Floyd

AU - Lockhart, Shawn R.

AU - Harris, Julie R.

AU - Fothergill, Annette

AU - Wickes, Brian

AU - Gober-Wilcox, Julie

AU - Massie, Larry

AU - Ku, T. S.Neil

AU - Firacative, Carolina

AU - Meyer, Wieland

AU - Lee, Samuel A.

PY - 2011/12/14

Y1 - 2011/12/14

N2 - We report a case of fatal disseminated infection with Cryptococcus gattii in a patient from New Mexico. The patient had no history of recent travel to known C. gattii-endemic areas. Multilocus sequence typing revealed that the isolate belonged to the major molecular type VGIII. Virulence studies in a mouse pulmonary model of infection demonstrated that the strain was less virulent than other C. gattii strains. This represents the first documented case of C. gattii likely acquired in New Mexico.

AB - We report a case of fatal disseminated infection with Cryptococcus gattii in a patient from New Mexico. The patient had no history of recent travel to known C. gattii-endemic areas. Multilocus sequence typing revealed that the isolate belonged to the major molecular type VGIII. Virulence studies in a mouse pulmonary model of infection demonstrated that the strain was less virulent than other C. gattii strains. This represents the first documented case of C. gattii likely acquired in New Mexico.

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UR - https://www.scopus.com/pages/publications/83355173222#tab=citedBy

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AN - SCOPUS:83355173222

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JO - PLOS ONE

JF - PLOS ONE

IS - 12

M1 - e28625

ER -

Fatal disseminated cryptococcus gattii infection in New Mexico

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