Exposure to pesticide mixtures and DNA damage among rice field workers

Marcela Eugenia Varona-Uribe, Sonia Díaz-Criollo, Ruth Marien Palma-Parra, Diana María Narváez, Sandra Patricia Carmona, Leonardo Briceño, Alvaro J. Idrovo

Resultado de la investigación: Contribución a una revistaArtículo

15 Citas (Scopus)

Resumen

This study describes the use of pesticides mixtures and their potential association with comet assay results in 223 rice field workers in Colombia. Thirty-one pesticides were quantified in blood, serum, and urine (15 organochlorines, 10 organophosphorus, 5 carbamates, and ethylenethiourea), and the comet assay was performed. Twenty-four (77.42%) pesticides were present in the workers. The use of the maximum-likelihood factor analysis identified 8 different mixtures. Afterwards, robust regressions were used to explore associations between the factors identified and the comet assay. Two groups of mixtures-α-benzene hexachloride (α-BHC), hexachlorobenzene (HCB), and β-BHC (β: 1.21, 95% confidence interval [CI]: 0.33-2.10) and pirimiphos-methyl, malathion, bromophos-methyl, and bromophos-ethyl (β: 11.97, 95% CI: 2.34-21.60)-were associated with a higher percentage of DNA damage and comet tail length, respectively. The findings suggest that exposure to pesticides varies greatly among rice field workers.

Idioma originalInglés estadounidense
Páginas (desde-hasta)3-9
Número de páginas7
PublicaciónArchives of Environmental and Occupational Health
Volumen71
N.º1
DOI
EstadoPublicada - ene 2 2016

All Science Journal Classification (ASJC) codes

  • Ciencias ambientales (todo)
  • Salud, toxicología y mutagénesis
  • Toxicología
  • Salud pública, medioambiental y laboral
  • Medicina (todo)

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