Exercise and glucose control in children with insulin resistance

prevalence of non-responders

C. Álvarez, R. Ramírez-Campillo, J. Cano-Montoya, R. Ramírez-Vélez, S. D.R. Harridge, A. M. Alonso-Martínez, M. Izquierdo

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

Antecedentes El entrenamiento con ejercicios mejora los resultados cardiometabólicos en "términos medios", pero hay poca información disponible en los niños acerca de la repercusión de la frecuencia/semana y la amplia variabilidad interindividual del entrenamiento con ejercicios reportada en adultos. Objetivos Se compararon los efectos del entrenamiento de resistencia (RT) y el entrenamiento a intervalos de alta intensidad (HIT), y la frecuencia "alta" y "baja" de entrenamiento/semana, para su efectividad en la disminución de los niveles de resistencia a la insulina (IR) en los escolares. Un segundo objetivo fue describir y comparar la prevalencia de los no respondedores (NR) entre las diferentes frecuencias del protocolo de entrenamiento. Métodos Cincuenta y tres escolares con IR fueron asignados aleatoriamente en cuatro grupos: RT a alta frecuencia (tres veces por semana), HIT a alta frecuencia, RT a baja frecuencia (dos veces por semana) y HIT a baja frecuencia. La intervención duró 6 semanas. Se tomaron muestras de sangre y composición corporal, presión arterial y medidas de rendimiento antes y después de la intervención. Resultados La prevalencia de NRs fue similar entre los grupos RTHF y HITHF (25.0% vs. 25.0%, P > 0.05) y RTLF y HITLF (20.0% vs. 46.6%, P = 0.174) para disminuir la evaluación del modelo de homeostasis de IR. Sin embargo, se detectaron diferencias significativas en la prevalencia de NRs entre los grupos de RTHF y HITHF en la glucosa en ayunas (FGL) (18,7% vs. 58,3%, P < 0,031). 4. Conclusiones Tanto RT como HIT mejoran los parámetros de control de la glucosa en los escolares durante 6 semanas, pero sólo HIT es independiente de una frecuencia alta o baja de entrenamiento/semana. La prevalencia de NRs es similar para disminuir la evaluación del modelo de homeostasis de IR comparando cada modo de ejercicio en alta vs. baja frecuencia/semana. Sin embargo, tanto la RT de alta y baja frecuencia como la HIT producen diferencias en la prevalencia de NR para la LGF y otros resultados cardiometabólicos y de rendimiento.
Idioma originalEnglish (US)
PublicaciónPediatric obesity
DOI
EstadoPublished - sep 11 2018

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Health Policy
  • Nutrition and Dietetics
  • Public Health, Environmental and Occupational Health

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Álvarez, C., Ramírez-Campillo, R., Cano-Montoya, J., Ramírez-Vélez, R., Harridge, S. D. R., Alonso-Martínez, A. M., & Izquierdo, M. (2018). Exercise and glucose control in children with insulin resistance: prevalence of non-responders. Pediatric obesity. https://doi.org/10.1111/ijpo.12437
Álvarez, C. ; Ramírez-Campillo, R. ; Cano-Montoya, J. ; Ramírez-Vélez, R. ; Harridge, S. D.R. ; Alonso-Martínez, A. M. ; Izquierdo, M. / Exercise and glucose control in children with insulin resistance : prevalence of non-responders. En: Pediatric obesity. 2018.
@article{99615b102d4c4253a80a52ba8039d64c,
title = "Exercise and glucose control in children with insulin resistance: prevalence of non-responders",
abstract = "Background: Exercise training improves cardiometabolic outcomes in ‘mean terms’, but little information is available in children about the impact of the frequency/week and the wide inter-individual variability to exercise training reported in adults. Objectives: We compared the effects of resistance training (RT) and high-intensity interval training (HIT), and ‘high’ and ‘low’ frequency of training/week, for their effectiveness in decreasing insulin resistance (IR) levels in schoolchildren. A second aim was to decscribe and compare the prevalence of non-responders (NRs) between the different frequencies of training protocol. Methods: Fifty-three schoolchildren with IR were randomly assigned into four groups: RT at high frequency (three times/week), HIT at high frequency, RT at a low frequency (two times/week) and HIT at low frequency. The intervention lasted 6 weeks. Blood samples and body composition, blood pressure and performance measurements were taken before and after the intervention. Results: The prevalence of NRs was similar between the RTHF and HITHF (25.0{\%} vs. 25.0{\%}, P > 0.05) and RTLF and HITLF groups (20.0{\%} vs. 46.6{\%}, P = 0.174) for decreasing homeostasis model assessment of IR. However, significant differences in the prevalence of NRs were detected between RTHF and HITHF groups in fasting glucose (FGL) (18.7{\%} vs. 58.3{\%}, P < 0.031). Conclusions: Both RT and HIT improves the glucose control parameters in schoolchildren over 6 weeks, but only HIT is independent of a high or low frequency of training/week. The prevalence of NRs is similar for decreasing homeostasis model assessment of IR comparing each exercise mode in high vs. low frequency/week. However, both high- and low-frequency RT and HIT results in differences in the prevalence of NRs for FGL and other cardiometabolic and performance outcomes.",
author = "C. {\'A}lvarez and R. Ram{\'i}rez-Campillo and J. Cano-Montoya and R. Ram{\'i}rez-V{\'e}lez and Harridge, {S. D.R.} and Alonso-Mart{\'i}nez, {A. M.} and M. Izquierdo",
year = "2018",
month = "9",
day = "11",
doi = "10.1111/ijpo.12437",
language = "English (US)",
journal = "Pediatric obesity",
issn = "2047-6302",
publisher = "Wiley-Blackwell for the International Association for the Study of Obesity",

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Álvarez, C, Ramírez-Campillo, R, Cano-Montoya, J, Ramírez-Vélez, R, Harridge, SDR, Alonso-Martínez, AM & Izquierdo, M 2018, 'Exercise and glucose control in children with insulin resistance: prevalence of non-responders', Pediatric obesity. https://doi.org/10.1111/ijpo.12437

Exercise and glucose control in children with insulin resistance : prevalence of non-responders. / Álvarez, C.; Ramírez-Campillo, R.; Cano-Montoya, J.; Ramírez-Vélez, R.; Harridge, S. D.R.; Alonso-Martínez, A. M.; Izquierdo, M.

En: Pediatric obesity, 11.09.2018.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Exercise and glucose control in children with insulin resistance

T2 - prevalence of non-responders

AU - Álvarez, C.

AU - Ramírez-Campillo, R.

AU - Cano-Montoya, J.

AU - Ramírez-Vélez, R.

AU - Harridge, S. D.R.

AU - Alonso-Martínez, A. M.

AU - Izquierdo, M.

PY - 2018/9/11

Y1 - 2018/9/11

N2 - Background: Exercise training improves cardiometabolic outcomes in ‘mean terms’, but little information is available in children about the impact of the frequency/week and the wide inter-individual variability to exercise training reported in adults. Objectives: We compared the effects of resistance training (RT) and high-intensity interval training (HIT), and ‘high’ and ‘low’ frequency of training/week, for their effectiveness in decreasing insulin resistance (IR) levels in schoolchildren. A second aim was to decscribe and compare the prevalence of non-responders (NRs) between the different frequencies of training protocol. Methods: Fifty-three schoolchildren with IR were randomly assigned into four groups: RT at high frequency (three times/week), HIT at high frequency, RT at a low frequency (two times/week) and HIT at low frequency. The intervention lasted 6 weeks. Blood samples and body composition, blood pressure and performance measurements were taken before and after the intervention. Results: The prevalence of NRs was similar between the RTHF and HITHF (25.0% vs. 25.0%, P > 0.05) and RTLF and HITLF groups (20.0% vs. 46.6%, P = 0.174) for decreasing homeostasis model assessment of IR. However, significant differences in the prevalence of NRs were detected between RTHF and HITHF groups in fasting glucose (FGL) (18.7% vs. 58.3%, P < 0.031). Conclusions: Both RT and HIT improves the glucose control parameters in schoolchildren over 6 weeks, but only HIT is independent of a high or low frequency of training/week. The prevalence of NRs is similar for decreasing homeostasis model assessment of IR comparing each exercise mode in high vs. low frequency/week. However, both high- and low-frequency RT and HIT results in differences in the prevalence of NRs for FGL and other cardiometabolic and performance outcomes.

AB - Background: Exercise training improves cardiometabolic outcomes in ‘mean terms’, but little information is available in children about the impact of the frequency/week and the wide inter-individual variability to exercise training reported in adults. Objectives: We compared the effects of resistance training (RT) and high-intensity interval training (HIT), and ‘high’ and ‘low’ frequency of training/week, for their effectiveness in decreasing insulin resistance (IR) levels in schoolchildren. A second aim was to decscribe and compare the prevalence of non-responders (NRs) between the different frequencies of training protocol. Methods: Fifty-three schoolchildren with IR were randomly assigned into four groups: RT at high frequency (three times/week), HIT at high frequency, RT at a low frequency (two times/week) and HIT at low frequency. The intervention lasted 6 weeks. Blood samples and body composition, blood pressure and performance measurements were taken before and after the intervention. Results: The prevalence of NRs was similar between the RTHF and HITHF (25.0% vs. 25.0%, P > 0.05) and RTLF and HITLF groups (20.0% vs. 46.6%, P = 0.174) for decreasing homeostasis model assessment of IR. However, significant differences in the prevalence of NRs were detected between RTHF and HITHF groups in fasting glucose (FGL) (18.7% vs. 58.3%, P < 0.031). Conclusions: Both RT and HIT improves the glucose control parameters in schoolchildren over 6 weeks, but only HIT is independent of a high or low frequency of training/week. The prevalence of NRs is similar for decreasing homeostasis model assessment of IR comparing each exercise mode in high vs. low frequency/week. However, both high- and low-frequency RT and HIT results in differences in the prevalence of NRs for FGL and other cardiometabolic and performance outcomes.

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Álvarez C, Ramírez-Campillo R, Cano-Montoya J, Ramírez-Vélez R, Harridge SDR, Alonso-Martínez AM y otros. Exercise and glucose control in children with insulin resistance: prevalence of non-responders. Pediatric obesity. 2018 sep 11. https://doi.org/10.1111/ijpo.12437