Exercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trials

Antonio García-Hermoso, R. J.M. Ceballos-Ceballos, C. E. Poblete-Aro, A. C. Hackney, J. Mota, R. Ramírez-Vélez

Resultado de la investigación: Contribución a RevistaArtículo de revisión

16 Citas (Scopus)

Resumen

Background/Objective:Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.Subjects/Methods:A computerized search was made using three databases. The analysis was restricted to studies that examined the effect of exercise interventions on adipokines (adiponectin, leptin, resistin and visfatin) in pediatric obesity (6-18 years old). Fourteen randomized controlled trials (347 youths) were included. Weighted mean difference (WMD) and 95% confidence intervals were calculated.Results:Exercise was associated with a significant increase in adiponectin (WMD=0.882 μg ml -1, 95% CI, 0.271-1.493) but did not alter leptin and resistin level. Likewise, exercise intensity and change in body fat; as well as total exercise program duration, duration of the sessions, and change in body fat all significantly influenced the effect of exercise on adiponectin and leptin, respectively.Conclusions:Exercise seems to increase adiponectin levels in childhood obesity. Our results also suggested that exercise on its own, without the concomitant presence of changes in body composition levels, does not affect leptin levels.

Idioma originalEnglish (US)
Páginas (desde-hasta)475-482
Número de páginas8
PublicaciónInternational Journal of Obesity
Volumen41
N.º4
DOI
EstadoPublished - abr 1 2017

Huella dactilar

Adipokines
Pediatric Obesity
Meta-Analysis
Randomized Controlled Trials
Exercise
Adiponectin
Leptin
Resistin
Adipose Tissue
Nicotinamide Phosphoribosyltransferase
Body Composition
Insulin Resistance
Atherosclerosis
Databases
Confidence Intervals

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

Citar esto

García-Hermoso, A., Ceballos-Ceballos, R. J. M., Poblete-Aro, C. E., Hackney, A. C., Mota, J., & Ramírez-Vélez, R. (2017). Exercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trials. International Journal of Obesity, 41(4), 475-482. https://doi.org/10.1038/ijo.2016.230
García-Hermoso, Antonio ; Ceballos-Ceballos, R. J.M. ; Poblete-Aro, C. E. ; Hackney, A. C. ; Mota, J. ; Ramírez-Vélez, R. / Exercise, adipokines and pediatric obesity : A meta-analysis of randomized controlled trials. En: International Journal of Obesity. 2017 ; Vol. 41, N.º 4. pp. 475-482.
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abstract = "Background/Objective:Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.Subjects/Methods:A computerized search was made using three databases. The analysis was restricted to studies that examined the effect of exercise interventions on adipokines (adiponectin, leptin, resistin and visfatin) in pediatric obesity (6-18 years old). Fourteen randomized controlled trials (347 youths) were included. Weighted mean difference (WMD) and 95{\%} confidence intervals were calculated.Results:Exercise was associated with a significant increase in adiponectin (WMD=0.882 μg ml -1, 95{\%} CI, 0.271-1.493) but did not alter leptin and resistin level. Likewise, exercise intensity and change in body fat; as well as total exercise program duration, duration of the sessions, and change in body fat all significantly influenced the effect of exercise on adiponectin and leptin, respectively.Conclusions:Exercise seems to increase adiponectin levels in childhood obesity. Our results also suggested that exercise on its own, without the concomitant presence of changes in body composition levels, does not affect leptin levels.",
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García-Hermoso, A, Ceballos-Ceballos, RJM, Poblete-Aro, CE, Hackney, AC, Mota, J & Ramírez-Vélez, R 2017, 'Exercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trials', International Journal of Obesity, vol. 41, n.º 4, pp. 475-482. https://doi.org/10.1038/ijo.2016.230

Exercise, adipokines and pediatric obesity : A meta-analysis of randomized controlled trials. / García-Hermoso, Antonio; Ceballos-Ceballos, R. J.M.; Poblete-Aro, C. E.; Hackney, A. C.; Mota, J.; Ramírez-Vélez, R.

En: International Journal of Obesity, Vol. 41, N.º 4, 01.04.2017, p. 475-482.

Resultado de la investigación: Contribución a RevistaArtículo de revisión

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AU - García-Hermoso, Antonio

AU - Ceballos-Ceballos, R. J.M.

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AU - Hackney, A. C.

AU - Mota, J.

AU - Ramírez-Vélez, R.

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N2 - Background/Objective:Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.Subjects/Methods:A computerized search was made using three databases. The analysis was restricted to studies that examined the effect of exercise interventions on adipokines (adiponectin, leptin, resistin and visfatin) in pediatric obesity (6-18 years old). Fourteen randomized controlled trials (347 youths) were included. Weighted mean difference (WMD) and 95% confidence intervals were calculated.Results:Exercise was associated with a significant increase in adiponectin (WMD=0.882 μg ml -1, 95% CI, 0.271-1.493) but did not alter leptin and resistin level. Likewise, exercise intensity and change in body fat; as well as total exercise program duration, duration of the sessions, and change in body fat all significantly influenced the effect of exercise on adiponectin and leptin, respectively.Conclusions:Exercise seems to increase adiponectin levels in childhood obesity. Our results also suggested that exercise on its own, without the concomitant presence of changes in body composition levels, does not affect leptin levels.

AB - Background/Objective:Adipokines are involved in the etiology of diabetes, insulin resistance, and the development of atherosclerosis and other latent-onset complications. The objective of this meta-analysis was to determine the effectiveness of exercise interventions on adipokines in pediatric obesity.Subjects/Methods:A computerized search was made using three databases. The analysis was restricted to studies that examined the effect of exercise interventions on adipokines (adiponectin, leptin, resistin and visfatin) in pediatric obesity (6-18 years old). Fourteen randomized controlled trials (347 youths) were included. Weighted mean difference (WMD) and 95% confidence intervals were calculated.Results:Exercise was associated with a significant increase in adiponectin (WMD=0.882 μg ml -1, 95% CI, 0.271-1.493) but did not alter leptin and resistin level. Likewise, exercise intensity and change in body fat; as well as total exercise program duration, duration of the sessions, and change in body fat all significantly influenced the effect of exercise on adiponectin and leptin, respectively.Conclusions:Exercise seems to increase adiponectin levels in childhood obesity. Our results also suggested that exercise on its own, without the concomitant presence of changes in body composition levels, does not affect leptin levels.

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García-Hermoso A, Ceballos-Ceballos RJM, Poblete-Aro CE, Hackney AC, Mota J, Ramírez-Vélez R. Exercise, adipokines and pediatric obesity: A meta-analysis of randomized controlled trials. International Journal of Obesity. 2017 abr 1;41(4):475-482. https://doi.org/10.1038/ijo.2016.230