Epidemiology of a decade of Pediatric fatal burns in Colombia, South America

Maria Cristina Del Rosario Aldana; Norberto Navarrete

doi:10.1016/j.burns.2015.05.005

Epidemiology of a decade of Pediatric fatal burns in Colombia, South America

Maria Cristina Del Rosario Aldana, Norberto Navarrete

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

15 Citas (Scopus)

Resumen

Introducción y objetivo
El ácido tranexámico (ATX) es un fármaco antifibrinolítico utilizado para la reducción del sangrado en situaciones de riesgo de mortalidad como es el trauma. El objetivo es evaluar la efectividad y seguridad del ATX en la reducción del sangrado operatorio en la artroplastia de cadera mediante una revisión sistemática de la literatura.

Material y métodos
Se realizó una revisión sistemática de la literatura y un metaanálisis de estudios primarios tipo ensayos clínicos controlados. La búsqueda de la literatura fue realizada en MEDLINE, Embase, Cochrane, LILACS, SciELO y Google Scholar. La revisión fue propuesta y realizada por 2 revisores y los criterios de inclusión fueron: a) pacientes sometidos a artroplastia de cadera unilateral primaria; b) comparación de un grupo de tratamiento con ATX frente a un grupo de control que recibió un placebo o ningún tratamiento en absoluto; c) las medidas de resultado: pérdida sanguínea total, número de pacientes sometidos a transfusión alogénica y/o incidencia de complicaciones tromboembólicas. La búsqueda de estudios se realizó desde el año 1966 a junio de 2013.

Resultados
Un total de 16 estudios fueron contemplados para esta revisión, con 246 pacientes incluidos. Se evidenció en el desenlace de pérdida sanguínea total un efecto ponderado de diferencia de promedios a favor de TXA vs. control de los pacientes sometidos a artroplastia de cadera (−0,45 [p < 0,001, IC 95% −0,65 a −0,24]). Se estimó el riesgo relativo ponderado para el desenlace de requerimiento de transfusión alogénica, el cual evidenció una tendencia a favorecer al brazo de ATX con un número de pacientes que requieren menos transfusión alogénica en cirugía de cadera (0,8 [p < 0,02, IC 95% 0,57 a 1,11]), sin embargo, esta tendencia no fue estadísticamente significativa.

Limitaciones
Existe una diferencia notable en los métodos de medición para la cuantificación de las pérdidas sanguíneas totales entre los estudios. El desenlace de necesidad de transfusión no es significativo, probablemente por el número de eventos en el grupo de ATX.

Conclusiones
El ATX se puede considerar de uso rutinario en la artroplastia primaria de cadera para reducir la pérdida de sangre intra y posquirúrgica

Idioma original	Inglés estadounidense
Páginas (desde-hasta)	1587-1592
Número de páginas	6
Publicación	Burns
Volumen	41
N.º	7
DOI	https://doi.org/10.1016/j.burns.2015.05.005
Estado	Publicada - nov. 2015
Publicado de forma externa	Sí

Áreas temáticas de ASJC Scopus

Cirugía
Medicina de urgencias
Cuidados y vigilancia intensivos

Acceder al documento

10.1016/j.burns.2015.05.005

Otros archivos y enlaces

Citar esto

@article{14e7ea0a230b4ccf95be95b4672f8d2e,

title = "Epidemiology of a decade of Pediatric fatal burns in Colombia, South America",

abstract = "Background Burns represent a serious problem around the world especially in low- and middle-income countries. The aim was to determine the epidemiological characteristics, causes and mortality rate of burn deaths in the Colombian pediatric population as well as to guide future education and prevention programs. Methods We conducted an observational, analytical, retrospective population-based study. It was based upon official death certificate data using diagnosis codes for burns (scalds, thermal, electrical, intentional self-harm and not specified), that occurred between January 1, 2000 and December 31, 2009. Official death certificates of the pediatric population of up to 15 years of age were obtained from the National Administrative Department of Statistics. Results A total of 1197 fatal pediatric injuries related to burns were identified. The crude and adjusted mortality rate for burns in the pediatric population in Colombia during the length of the study was 0.899 and 0.912 per 100,000, respectively. The mortality rate tended to decrease (-5.17% annual) during the duration of the study. Children under 5 years of age were the most affected group (59.5%). Almost half of them died before arriving at a health facility (47.1%). Fire is the principal cause of death attributable to burns in Colombia, followed by electric burns and hot liquids. Conclusions This is a first step study in researching the epidemiological features of pediatric deaths after burns. The Public Health's strategies should be oriented toward community awareness about these kind of injuries, and to teach children and families about risk factors and first aid.",

author = "Aldana, {Maria Cristina Del Rosario} and Norberto Navarrete",

year = "2015",

month = nov,

doi = "10.1016/j.burns.2015.05.005",

language = "English (US)",

volume = "41",

pages = "1587--1592",

journal = "Burns",

issn = "0305-4179",

publisher = "Elsevier Limited",

number = "7",

}

TY - JOUR

T1 - Epidemiology of a decade of Pediatric fatal burns in Colombia, South America

AU - Aldana, Maria Cristina Del Rosario

AU - Navarrete, Norberto

PY - 2015/11

Y1 - 2015/11

N2 - Background Burns represent a serious problem around the world especially in low- and middle-income countries. The aim was to determine the epidemiological characteristics, causes and mortality rate of burn deaths in the Colombian pediatric population as well as to guide future education and prevention programs. Methods We conducted an observational, analytical, retrospective population-based study. It was based upon official death certificate data using diagnosis codes for burns (scalds, thermal, electrical, intentional self-harm and not specified), that occurred between January 1, 2000 and December 31, 2009. Official death certificates of the pediatric population of up to 15 years of age were obtained from the National Administrative Department of Statistics. Results A total of 1197 fatal pediatric injuries related to burns were identified. The crude and adjusted mortality rate for burns in the pediatric population in Colombia during the length of the study was 0.899 and 0.912 per 100,000, respectively. The mortality rate tended to decrease (-5.17% annual) during the duration of the study. Children under 5 years of age were the most affected group (59.5%). Almost half of them died before arriving at a health facility (47.1%). Fire is the principal cause of death attributable to burns in Colombia, followed by electric burns and hot liquids. Conclusions This is a first step study in researching the epidemiological features of pediatric deaths after burns. The Public Health's strategies should be oriented toward community awareness about these kind of injuries, and to teach children and families about risk factors and first aid.

AB - Background Burns represent a serious problem around the world especially in low- and middle-income countries. The aim was to determine the epidemiological characteristics, causes and mortality rate of burn deaths in the Colombian pediatric population as well as to guide future education and prevention programs. Methods We conducted an observational, analytical, retrospective population-based study. It was based upon official death certificate data using diagnosis codes for burns (scalds, thermal, electrical, intentional self-harm and not specified), that occurred between January 1, 2000 and December 31, 2009. Official death certificates of the pediatric population of up to 15 years of age were obtained from the National Administrative Department of Statistics. Results A total of 1197 fatal pediatric injuries related to burns were identified. The crude and adjusted mortality rate for burns in the pediatric population in Colombia during the length of the study was 0.899 and 0.912 per 100,000, respectively. The mortality rate tended to decrease (-5.17% annual) during the duration of the study. Children under 5 years of age were the most affected group (59.5%). Almost half of them died before arriving at a health facility (47.1%). Fire is the principal cause of death attributable to burns in Colombia, followed by electric burns and hot liquids. Conclusions This is a first step study in researching the epidemiological features of pediatric deaths after burns. The Public Health's strategies should be oriented toward community awareness about these kind of injuries, and to teach children and families about risk factors and first aid.

UR - http://www.scopus.com/inward/record.url?scp=84945444919&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84945444919&partnerID=8YFLogxK

U2 - 10.1016/j.burns.2015.05.005

DO - 10.1016/j.burns.2015.05.005

M3 - Article

C2 - 26059049

AN - SCOPUS:84945444919

SN - 0305-4179

VL - 41

SP - 1587

EP - 1592

JO - Burns

JF - Burns

IS - 7

ER -

Epidemiology of a decade of Pediatric fatal burns in Colombia, South America

Resumen

Áreas temáticas de ASJC Scopus

Acceder al documento

Otros archivos y enlaces

Huella

Citar esto