© All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.Introduction: The retention of students in Medicine involves development of strategies aimed at reducing academic desertion. Academic Support Program of the Universidad del Rosario, has contributed to this achievement from accompanying students in their learning. Objective: The aim of this study was to analyze the success and quality in academic promotion of students from Health Sciences at the University of Rosario, who entered the Strengthening Program, and previously lost their enrollment in Medicine because Biochemistry subjects. Methods: Census study that includes all students enrolled in the program (113) with reinforcement in Biochemistry subjects from the first half of 2008 to second in 2012. Results: 58% (n = 66) of students remained and obtaining readmission to the University and active status likewise undergraduate students in the medical career. The highest number was registered in the subjects Biochemistry reinforcement I and II: 42% (n = 58) and 50% (n = 56) respectively. 18% of those who stayed in college, exceeded the parameter of good academic quality, with notes ≥ 4, 0 in these subjects. Conclusions: Since Biochemistry context, the Strengthening Program has contributed to student retention in the medical career and also according to the challenge of public policy. The loss of quota for poor academic performance 21.8% (n = 87) of students who were readmitted to undergraduate indicates the orientation of activities influencing factors such as social isolation, family or health problems, and vocational guidance.