Clinical Insights: Antimicrobial Therapy for Infectious Uveitis

Evangeline Leong, Carlos Cifuentes-González, Jeremy Hu Y. W, Ramar Perumal Samy, Moncef Khairallah, William Rojas-Carabali, Ikhwanuliman Putera, Alejandra de-la-Torre, Rupesh Agrawal

Producción científica: Contribución a una revistaArtículo de revisiónrevisión exhaustiva

Resumen

Infectious uveitis is a major global cause of vision impairment. Despite the eye’s immune privilege, afforded by the blood-ocular barrier that restricts microbial entry, several pathogens such as bacteria, viruses, fungi, and parasites can still infiltrate and cause ocular infections and complications. Clinicians often encounter significant challenges in treating infectious uveitis due to limited or ineffective treatment options. Modern molecular techniques and imaging can aid in diagnosing and assessing intraocular infections. Various antimicrobial therapies exist, spanning topical and systemic treatments, but these are constrained by issues like drug concentration, penetration, effective duration, toxicity, and side effects. Treatment approaches also differ based on the infection’s etiology. This review provides recent updates on antimicrobial therapies from a clinical perspective, covering topical, systemic, and regional treatments for infectious uveitis.

Idioma originalInglés estadounidense
PublicaciónOcular Immunology and Inflammation
DOI
EstadoEn prensa - 2024
Publicado de forma externa

Áreas temáticas de ASJC Scopus

  • Inmulogía y alergología
  • Oftalmología

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