Circulation of Streptococcus pneumoniae clone Colombia5 ST289 in nine Latin American countries

Carolina Firacative, Jaime Moreno, Patricia Resales, Aurora Maldonado, Jacqueline Sánchez, Carmen Pesantes, Sergio López, Markela De Quinzada, Gustavo Chamorro, Sara Morales, Enza Spadola, Jean Marc Gabastou, Elizabeth Castañeda

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

8 Citas (Scopus)

Resumen

Objective. To determine genetic relatedness of clone Colombia5 ST289 with invasive Streptococcus pneumoniae serotype 5 isolates recovered in nine Latin American countries. Methods. Forty-four invasive S. pneumoniae serotype 5 isolates recovered from children under 5 years of age in Bolivia, Chile, Dominican Republic, Ecuador, Nicaragua, Panama, Paraguay, Peru, and Venezuela were studied. Pulsed-field gel electrophoresis patterns of DNA treated with Smal restriction enzyme were classified using Tenover's criteria and analyzed with the Fingerprinting II program to determine their genetic relatedness with the Colombian clone. Results. All isolates had a genetic similarity of 78.5% or more with the Colombian clone. Thirteen electrophoretic subtypes derived of pattern A were identified, and five of them (A5, A6, A8, A13, All) comprised 61.4% of the isolates. Conclusions. Clone Colombia 5 ST289 is disseminated in Latin America. This is important because S. pneumoniae serotype 5 frequently causes invasive disease in the region and is associated with trimethoprim-sulfamethoxazole resistance.

Idioma originalInglés estadounidense
Páginas (desde-hasta)337-343
Número de páginas7
PublicaciónRevista Panamericana de Salud Publica/Pan American Journal of Public Health
Volumen25
N.º4
DOI
EstadoPublicada - abr 2009
Publicado de forma externa

All Science Journal Classification (ASJC) codes

  • Salud pública, medioambiental y laboral

Huella Profundice en los temas de investigación de 'Circulation of <i>Streptococcus pneumoniae</i> clone Colombia<sup>5</sup> ST289 in nine Latin American countries'. En conjunto forman una huella única.

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