Cardiovascular disease in Latin American patients with systemic lupus erythematosus: A cross-sectional study and a systematic review

Jenny Amaya-Amaya, Juan Camilo Sarmiento-Monroy, Julián Caro-Moreno, Nicolás Molano-González, Rubén D. Mantilla, Adriana Rojas-Villarraga, Juan Manuel Anaya

Resultado de la investigación: Contribución a RevistaArtículo

15 Citas (Scopus)

Resumen

Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a cross-sectional analytical study was conducted in 310 Colombian patients with SLE in whom CVD was assessed. Associated factors were examined by multivariate regression analyses. Second, a systematic review of the literature on CVD in SLE in LA was performed. Results. There were 133 (36.5%) Colombian SLE patients with CVD. Dyslipidemia, smoking, coffee consumption, and pleural effusion were positively associated with CVD. An independent effect of coffee consumption and cigarette on CVD was found regardless of gender and duration of disease. In the systematic review, 60 articles fulfilling the eligibility criteria were included. A wide range of CVD prevalence was found (4%-79.5%). Several studies reported ancestry, genetic factors, and polyautoimmunity as novel risk factors for such a condition. Conclusions. A high rate of CVD is observed in LA patients with SLE. Awareness of the observed risk factors should encourage preventive population strategies for CVD in patients with SLE aimed at facilitating the suppression of cigarette smoking and coffee consumption as well as at the tight control of dyslipidemia and other modifiable risk factors. © 2013 Jenny Amaya-Amaya et al.
Idioma originalEnglish (US)
PublicaciónAutoimmune Diseases
Volumen2013
DOI
EstadoPublished - 2013

Huella dactilar

Systemic Lupus Erythematosus
Cardiovascular Diseases
Cross-Sectional Studies
Coffee
Dyslipidemias
Smoking
Pleural Effusion
Tobacco Products
Multivariate Analysis
Regression Analysis
Population

Citar esto

Amaya-Amaya, Jenny ; Sarmiento-Monroy, Juan Camilo ; Caro-Moreno, Julián ; Molano-González, Nicolás ; Mantilla, Rubén D. ; Rojas-Villarraga, Adriana ; Anaya, Juan Manuel. / Cardiovascular disease in Latin American patients with systemic lupus erythematosus: A cross-sectional study and a systematic review. En: Autoimmune Diseases. 2013 ; Vol. 2013.
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title = "Cardiovascular disease in Latin American patients with systemic lupus erythematosus: A cross-sectional study and a systematic review",
abstract = "Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a cross-sectional analytical study was conducted in 310 Colombian patients with SLE in whom CVD was assessed. Associated factors were examined by multivariate regression analyses. Second, a systematic review of the literature on CVD in SLE in LA was performed. Results. There were 133 (36.5{\%}) Colombian SLE patients with CVD. Dyslipidemia, smoking, coffee consumption, and pleural effusion were positively associated with CVD. An independent effect of coffee consumption and cigarette on CVD was found regardless of gender and duration of disease. In the systematic review, 60 articles fulfilling the eligibility criteria were included. A wide range of CVD prevalence was found (4{\%}-79.5{\%}). Several studies reported ancestry, genetic factors, and polyautoimmunity as novel risk factors for such a condition. Conclusions. A high rate of CVD is observed in LA patients with SLE. Awareness of the observed risk factors should encourage preventive population strategies for CVD in patients with SLE aimed at facilitating the suppression of cigarette smoking and coffee consumption as well as at the tight control of dyslipidemia and other modifiable risk factors. {\circledC} 2013 Jenny Amaya-Amaya et al.",
author = "Jenny Amaya-Amaya and Sarmiento-Monroy, {Juan Camilo} and Juli{\'a}n Caro-Moreno and Nicol{\'a}s Molano-Gonz{\'a}lez and Mantilla, {Rub{\'e}n D.} and Adriana Rojas-Villarraga and Anaya, {Juan Manuel}",
year = "2013",
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journal = "Autoimmune Diseases",
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Cardiovascular disease in Latin American patients with systemic lupus erythematosus: A cross-sectional study and a systematic review. / Amaya-Amaya, Jenny; Sarmiento-Monroy, Juan Camilo; Caro-Moreno, Julián; Molano-González, Nicolás; Mantilla, Rubén D.; Rojas-Villarraga, Adriana; Anaya, Juan Manuel.

En: Autoimmune Diseases, Vol. 2013, 2013.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Cardiovascular disease in Latin American patients with systemic lupus erythematosus: A cross-sectional study and a systematic review

AU - Amaya-Amaya, Jenny

AU - Sarmiento-Monroy, Juan Camilo

AU - Caro-Moreno, Julián

AU - Molano-González, Nicolás

AU - Mantilla, Rubén D.

AU - Rojas-Villarraga, Adriana

AU - Anaya, Juan Manuel

PY - 2013

Y1 - 2013

N2 - Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a cross-sectional analytical study was conducted in 310 Colombian patients with SLE in whom CVD was assessed. Associated factors were examined by multivariate regression analyses. Second, a systematic review of the literature on CVD in SLE in LA was performed. Results. There were 133 (36.5%) Colombian SLE patients with CVD. Dyslipidemia, smoking, coffee consumption, and pleural effusion were positively associated with CVD. An independent effect of coffee consumption and cigarette on CVD was found regardless of gender and duration of disease. In the systematic review, 60 articles fulfilling the eligibility criteria were included. A wide range of CVD prevalence was found (4%-79.5%). Several studies reported ancestry, genetic factors, and polyautoimmunity as novel risk factors for such a condition. Conclusions. A high rate of CVD is observed in LA patients with SLE. Awareness of the observed risk factors should encourage preventive population strategies for CVD in patients with SLE aimed at facilitating the suppression of cigarette smoking and coffee consumption as well as at the tight control of dyslipidemia and other modifiable risk factors. © 2013 Jenny Amaya-Amaya et al.

AB - Objective. This study was performed to determine the prevalence of and associated risk factors for cardiovascular disease (CVD) in Latin American (LA) patients with systemic lupus erythematosus (SLE). Methods. First, a cross-sectional analytical study was conducted in 310 Colombian patients with SLE in whom CVD was assessed. Associated factors were examined by multivariate regression analyses. Second, a systematic review of the literature on CVD in SLE in LA was performed. Results. There were 133 (36.5%) Colombian SLE patients with CVD. Dyslipidemia, smoking, coffee consumption, and pleural effusion were positively associated with CVD. An independent effect of coffee consumption and cigarette on CVD was found regardless of gender and duration of disease. In the systematic review, 60 articles fulfilling the eligibility criteria were included. A wide range of CVD prevalence was found (4%-79.5%). Several studies reported ancestry, genetic factors, and polyautoimmunity as novel risk factors for such a condition. Conclusions. A high rate of CVD is observed in LA patients with SLE. Awareness of the observed risk factors should encourage preventive population strategies for CVD in patients with SLE aimed at facilitating the suppression of cigarette smoking and coffee consumption as well as at the tight control of dyslipidemia and other modifiable risk factors. © 2013 Jenny Amaya-Amaya et al.

U2 - 10.1155/2013/794383

DO - 10.1155/2013/794383

M3 - Article

C2 - 24294522

VL - 2013

JO - Autoimmune Diseases

JF - Autoimmune Diseases

SN - 2090-0422

ER -