Autoimmune thyroid disease in rheumatoid arthritis: a global perspective

Jorge Cárdenas-Roldán, Jenny Amaya-Amaya, Juan Castellanos-De La Hoz, Juliana Giraldo-Villamil, Gladys Montoya-Ortiz, Paola Cruz-Tapias, Adriana Rojas-Villarraga, Rubén-Darío Mantilla, Juan-Manuel Anaya

Resultado de la investigación: Contribución a RevistaArtículo

Resumen

Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.

Idioma originalEnglish (US)
Páginas (desde-hasta)864907
PublicaciónArthritis
Volumen2012
DOI
EstadoPublished - 2012

Huella dactilar

Thyroid Diseases
Autoimmune Diseases
Rheumatoid Arthritis
Public Policy
Health Policy
Autoantibodies
Type 2 Diabetes Mellitus
Body Mass Index
Thrombosis
Cardiovascular Diseases
Multivariate Analysis
Public Health
Antibodies
Enzymes

Citar esto

Cárdenas-Roldán, J., Amaya-Amaya, J., Castellanos-De La Hoz, J., Giraldo-Villamil, J., Montoya-Ortiz, G., Cruz-Tapias, P., ... Anaya, J-M. (2012). Autoimmune thyroid disease in rheumatoid arthritis: a global perspective. Arthritis, 2012, 864907. https://doi.org/10.1155/2012/864907
Cárdenas-Roldán, Jorge ; Amaya-Amaya, Jenny ; Castellanos-De La Hoz, Juan ; Giraldo-Villamil, Juliana ; Montoya-Ortiz, Gladys ; Cruz-Tapias, Paola ; Rojas-Villarraga, Adriana ; Mantilla, Rubén-Darío ; Anaya, Juan-Manuel. / Autoimmune thyroid disease in rheumatoid arthritis : a global perspective. En: Arthritis. 2012 ; Vol. 2012. pp. 864907.
@article{aaf1371194804e2d918577fcae02afc9,
title = "Autoimmune thyroid disease in rheumatoid arthritis: a global perspective",
abstract = "Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8{\%} while the presence of antibodies was 37.8{\%} for antithyroperoxidase enzyme (TPOAb) and 20.8{\%} for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5{\%} to 27{\%}. Autoantibody prevalence ranges from 6{\%} to 31{\%} for TgAb, 5{\%} to 37{\%} for TPOAb, and from 11.4{\%} to 32{\%} for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.",
author = "Jorge C{\'a}rdenas-Rold{\'a}n and Jenny Amaya-Amaya and {Castellanos-De La Hoz}, Juan and Juliana Giraldo-Villamil and Gladys Montoya-Ortiz and Paola Cruz-Tapias and Adriana Rojas-Villarraga and Rub{\'e}n-Dar{\'i}o Mantilla and Juan-Manuel Anaya",
year = "2012",
doi = "10.1155/2012/864907",
language = "English (US)",
volume = "2012",
pages = "864907",
journal = "Arthritis",
issn = "2090-1984",
publisher = "Hindawi Publishing Corporation",

}

Cárdenas-Roldán, J, Amaya-Amaya, J, Castellanos-De La Hoz, J, Giraldo-Villamil, J, Montoya-Ortiz, G, Cruz-Tapias, P, Rojas-Villarraga, A, Mantilla, R-D & Anaya, J-M 2012, 'Autoimmune thyroid disease in rheumatoid arthritis: a global perspective', Arthritis, vol. 2012, pp. 864907. https://doi.org/10.1155/2012/864907

Autoimmune thyroid disease in rheumatoid arthritis : a global perspective. / Cárdenas-Roldán, Jorge; Amaya-Amaya, Jenny; Castellanos-De La Hoz, Juan; Giraldo-Villamil, Juliana; Montoya-Ortiz, Gladys; Cruz-Tapias, Paola; Rojas-Villarraga, Adriana; Mantilla, Rubén-Darío; Anaya, Juan-Manuel.

En: Arthritis, Vol. 2012, 2012, p. 864907.

Resultado de la investigación: Contribución a RevistaArtículo

TY - JOUR

T1 - Autoimmune thyroid disease in rheumatoid arthritis

T2 - a global perspective

AU - Cárdenas-Roldán, Jorge

AU - Amaya-Amaya, Jenny

AU - Castellanos-De La Hoz, Juan

AU - Giraldo-Villamil, Juliana

AU - Montoya-Ortiz, Gladys

AU - Cruz-Tapias, Paola

AU - Rojas-Villarraga, Adriana

AU - Mantilla, Rubén-Darío

AU - Anaya, Juan-Manuel

PY - 2012

Y1 - 2012

N2 - Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.

AB - Objective. To determine the prevalence and impact of autoimmune thyroid disease (AITD) in patients with rheumatoid arthritis (RA). Methods. Eight-hundred patients were included. The association between AITD and RA was analyzed was analyzed by bivariate and multivariate analysis. In addition, a literature review was done focusing on geographical variations. Results. In our cohort the prevalence of AITD was 9.8% while the presence of antibodies was 37.8% for antithyroperoxidase enzyme (TPOAb) and 20.8% for antithyroglobulin protein (TgAb). The presence of type 2 diabetes, thrombosis, abnormal body mass index, and a high educational level was positively associated with AITD. The literature review disclosed a geographical variation of AITD in RA ranging from 0.5% to 27%. Autoantibody prevalence ranges from 6% to 31% for TgAb, 5% to 37% for TPOAb, and from 11.4% to 32% for the presence of either of the two. Conclusion. AITD is not uncommon in RA and should be systematically assessed since it is a risk factor for developing diabetes and cardiovascular disease. These results may help to further study the common mechanisms of autoimmune diseases, to improve patients' outcome, and to define public health policies. An international consensus to accurately diagnose AITD is warranted.

U2 - 10.1155/2012/864907

DO - 10.1155/2012/864907

M3 - Article

C2 - 23209899

VL - 2012

SP - 864907

JO - Arthritis

JF - Arthritis

SN - 2090-1984

ER -

Cárdenas-Roldán J, Amaya-Amaya J, Castellanos-De La Hoz J, Giraldo-Villamil J, Montoya-Ortiz G, Cruz-Tapias P y otros. Autoimmune thyroid disease in rheumatoid arthritis: a global perspective. Arthritis. 2012;2012:864907. https://doi.org/10.1155/2012/864907