Are autoimmune diseases predictable?

Gabriel J. Tobón, Jacques Olivier Pers, Carlos A. Cañas, Adriana Rojas-Villarraga, Pierre Youinou, Juan Manuel Anaya

Resultado de la investigación: Contribución a RevistaRevisión Literaria

35 Citas (Scopus)

Resumen

Autoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis. In addition to serum antibodies, genetic susceptibility factors may predict the future development of the disease. Currently, prediction in type 1 diabetes is the most accurate, with the analysis of genetic susceptibility factors in first-degree relatives of patients and several autoantibody tests. In the future, multiple antibodies test, in combination with the analysis of genetics, epigenetics and immunological anomalies in fine models may allow the precise prediction in autoimmune diseases. Prevention measures might thus be introduced as an attempt to avoid or delay the disease. © 2011 Elsevier B.V.
Idioma originalEnglish (US)
Páginas (desde-hasta)259-266
Número de páginas8
PublicaciónAutoimmunity Reviews
DOI
EstadoPublished - feb 1 2012

Huella dactilar

Autoimmune Diseases
Genetic Predisposition to Disease
Autoantibodies
Antibodies
Serum
Type 1 Diabetes Mellitus
Epigenomics

Citar esto

Tobón, G. J., Pers, J. O., Cañas, C. A., Rojas-Villarraga, A., Youinou, P., & Anaya, J. M. (2012). Are autoimmune diseases predictable? Autoimmunity Reviews, 259-266. https://doi.org/10.1016/j.autrev.2011.10.004
Tobón, Gabriel J. ; Pers, Jacques Olivier ; Cañas, Carlos A. ; Rojas-Villarraga, Adriana ; Youinou, Pierre ; Anaya, Juan Manuel. / Are autoimmune diseases predictable?. En: Autoimmunity Reviews. 2012 ; pp. 259-266.
@article{4d6543f6554842bebc8f0f1c91bd920e,
title = "Are autoimmune diseases predictable?",
abstract = "Autoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis. In addition to serum antibodies, genetic susceptibility factors may predict the future development of the disease. Currently, prediction in type 1 diabetes is the most accurate, with the analysis of genetic susceptibility factors in first-degree relatives of patients and several autoantibody tests. In the future, multiple antibodies test, in combination with the analysis of genetics, epigenetics and immunological anomalies in fine models may allow the precise prediction in autoimmune diseases. Prevention measures might thus be introduced as an attempt to avoid or delay the disease. {\circledC} 2011 Elsevier B.V.",
author = "Tob{\'o}n, {Gabriel J.} and Pers, {Jacques Olivier} and Ca{\~n}as, {Carlos A.} and Adriana Rojas-Villarraga and Pierre Youinou and Anaya, {Juan Manuel}",
year = "2012",
month = "2",
day = "1",
doi = "10.1016/j.autrev.2011.10.004",
language = "English (US)",
pages = "259--266",
journal = "Autoimmunity Reviews",
issn = "1568-9972",
publisher = "Elsevier",

}

Tobón, GJ, Pers, JO, Cañas, CA, Rojas-Villarraga, A, Youinou, P & Anaya, JM 2012, 'Are autoimmune diseases predictable?', Autoimmunity Reviews, pp. 259-266. https://doi.org/10.1016/j.autrev.2011.10.004

Are autoimmune diseases predictable? / Tobón, Gabriel J.; Pers, Jacques Olivier; Cañas, Carlos A.; Rojas-Villarraga, Adriana; Youinou, Pierre; Anaya, Juan Manuel.

En: Autoimmunity Reviews, 01.02.2012, p. 259-266.

Resultado de la investigación: Contribución a RevistaRevisión Literaria

TY - JOUR

T1 - Are autoimmune diseases predictable?

AU - Tobón, Gabriel J.

AU - Pers, Jacques Olivier

AU - Cañas, Carlos A.

AU - Rojas-Villarraga, Adriana

AU - Youinou, Pierre

AU - Anaya, Juan Manuel

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Autoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis. In addition to serum antibodies, genetic susceptibility factors may predict the future development of the disease. Currently, prediction in type 1 diabetes is the most accurate, with the analysis of genetic susceptibility factors in first-degree relatives of patients and several autoantibody tests. In the future, multiple antibodies test, in combination with the analysis of genetics, epigenetics and immunological anomalies in fine models may allow the precise prediction in autoimmune diseases. Prevention measures might thus be introduced as an attempt to avoid or delay the disease. © 2011 Elsevier B.V.

AB - Autoimmune diseases are complex diseases resulting of the interaction between both genetics and environmental factors over time. Different phases in the development of autoimmune diseases are characterized by the detection of serum autoantibodies several months or years before the onset of clinical manifestations and subsequent diagnosis. In addition to serum antibodies, genetic susceptibility factors may predict the future development of the disease. Currently, prediction in type 1 diabetes is the most accurate, with the analysis of genetic susceptibility factors in first-degree relatives of patients and several autoantibody tests. In the future, multiple antibodies test, in combination with the analysis of genetics, epigenetics and immunological anomalies in fine models may allow the precise prediction in autoimmune diseases. Prevention measures might thus be introduced as an attempt to avoid or delay the disease. © 2011 Elsevier B.V.

U2 - 10.1016/j.autrev.2011.10.004

DO - 10.1016/j.autrev.2011.10.004

M3 - Literature review

SP - 259

EP - 266

JO - Autoimmunity Reviews

JF - Autoimmunity Reviews

SN - 1568-9972

ER -

Tobón GJ, Pers JO, Cañas CA, Rojas-Villarraga A, Youinou P, Anaya JM. Are autoimmune diseases predictable? Autoimmunity Reviews. 2012 feb 1;259-266. https://doi.org/10.1016/j.autrev.2011.10.004