Resumen
Antecedentes. Se ha encontrado una ley exponencial para los sistemas dinámicos caóticos cardíacos que logra cuantificar las diferencias entre dinámicas cardíacas normales y aquellas con enfermedad aguda, así como la evolución entre estos estados.
Objetivo. Confirmar la aplicabilidad clínica de la metodología desarrollada a partir de la ley matemática para la dinámica cardiaca en dinámicas con arritmia.
Materiales y métodos. Se analizaron 60 holter, 10 correspondían a sujetos normales y 50 con diferentes tipos de arritmias. Para cada holter se construyó un atractor, se midió su dimensión fractal y ocupación espacial. Se aplicó la evaluación matemática para diferenciar dinámicas cardíacas normales de enfermas y en proceso de evolución. Se calculó la sensibilidad, especificidad y coeficiente Kappa.
Resultados. La evaluación matemática diferenció los espacios de ocupación, normalidad, enfermedad aguda y evolución entre estos estados. Los valores de sensibilidad y especificidad fueron de 100% y el coeficiente Kappa fue de 1.
Conclusiones. Se evidenció la aplicabilidad clínica de la metodología para casos con arritmias, siendo capaz de detectar cambios en la dinámica que no son clasificados como patológicos clínicamente.
| Idioma original | English (US) |
|---|---|
| Páginas (desde-hasta) | 539-546 |
| Número de páginas | 8 |
| Publicación | Revista Facultad de Medicina |
| Volumen | 62 |
| N.º | 4 |
| DOI | |
| Estado | Published - ene 1 2014 |
| Publicado de forma externa | Sí |
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Application of the chaotic power law to the study of cardiac dynamics in patients with arrhythmias. / Rodríguez-Velásquez, Javier; Prieto, Signed; Domínguez, Darío; Correa, Catalina; Melo, Martha; Pardo, Juan; Mendoza, Fernán; Victoria Rodríguez, Ligia; Cardona, Diana Margarita; Méndez, Laura.
En: Revista Facultad de Medicina, Vol. 62, N.º 4, 01.01.2014, p. 539-546.Resultado de la investigación: Contribución a Revista › Artículo
TY - JOUR
T1 - Application of the chaotic power law to the study of cardiac dynamics in patients with arrhythmias
AU - Rodríguez-Velásquez, Javier
AU - Prieto, Signed
AU - Domínguez, Darío
AU - Correa, Catalina
AU - Melo, Martha
AU - Pardo, Juan
AU - Mendoza, Fernán
AU - Victoria Rodríguez, Ligia
AU - Cardona, Diana Margarita
AU - Méndez, Laura
PY - 2014/1/1
Y1 - 2014/1/1
N2 - © 2014, Universidad Nacional de Colombia. All rights reserved.Background. An exponential law for chaotic cardiac dynamics, found previously, allows the quantification of the differences between normal cardiac dynamics and those with acute diseases, as well as the cardiac dynamics of the evolution between these states. Objective. To confirm the clinical applicability of the developed methodology through the mathematical law for cardiac dynamics in dynamics with arrhythmias. Materials and methods. 60 Holter electrocardiograms were analyzed, 10 corresponded to normal subjects, and 50 to subjects with different arrhythmias. For each Holter, an attractor was performed, and its fractal dimension and spatial occupancy were measured. A mathematical evaluation was applied in order to differentiate normal dynamics from pathological ones. Sensitivity, specificity and the Kappa coefficient were calculated. Results. The mathematical evaluation differentiated occupation spaces, normal dynamics, acute illness dynamics, and evolution between these states. The sensitivity and specificity values were 100%, and the Kappa coefficient was 1. Conclusions. The clinical applicability of the methodology for cases with arrhythmia was shown. It is also applicable for the detection of changes in dynamics that are not classified clinically as pathological.
AB - © 2014, Universidad Nacional de Colombia. All rights reserved.Background. An exponential law for chaotic cardiac dynamics, found previously, allows the quantification of the differences between normal cardiac dynamics and those with acute diseases, as well as the cardiac dynamics of the evolution between these states. Objective. To confirm the clinical applicability of the developed methodology through the mathematical law for cardiac dynamics in dynamics with arrhythmias. Materials and methods. 60 Holter electrocardiograms were analyzed, 10 corresponded to normal subjects, and 50 to subjects with different arrhythmias. For each Holter, an attractor was performed, and its fractal dimension and spatial occupancy were measured. A mathematical evaluation was applied in order to differentiate normal dynamics from pathological ones. Sensitivity, specificity and the Kappa coefficient were calculated. Results. The mathematical evaluation differentiated occupation spaces, normal dynamics, acute illness dynamics, and evolution between these states. The sensitivity and specificity values were 100%, and the Kappa coefficient was 1. Conclusions. The clinical applicability of the methodology for cases with arrhythmia was shown. It is also applicable for the detection of changes in dynamics that are not classified clinically as pathological.
U2 - 10.15446/revfacmed.v62n4.43444
DO - 10.15446/revfacmed.v62n4.43444
M3 - Article
VL - 62
SP - 539
EP - 546
JO - Revista de la Facultad de Medicina
JF - Revista de la Facultad de Medicina
SN - 0120-0011
IS - 4
ER -