Implicación de los alelos CYP2C9 en la efectividad y seguridad del tratamiento de epilepsia con fenitoína

Medicina y ciencias biológicas

1. Phenytoin 100%
2. Pharmacogenetics 79%
3. Cytochrome P-450 CYP2C9 70%
4. Epilepsy 59%
5. Alleles 38%
6. Anticonvulsants 33%
7. Phenotype 31%
8. Pharmaceutical Preparations 29%
9. Genes 21%
10. Gene Amplification 20%
11. Cytochromes 20%
12. Metabolome 19%
13. Genetic Polymorphisms 18%
14. Informed Consent 17%
15. Drug-Related Side Effects and Adverse Reactions 16%
16. Health Care Costs 15%
17. Sample Size 15%
18. Therapeutics 14%
19. Language 13%
20. Population 13%
21. Medicine 12%
22. Physicians 11%
23. Polymerase Chain Reaction 10%
24. Safety 10%
25. DNA 9%
26. Enzymes 9%
27. Health 8%
28. Serum 7%