Vitaminas B neurotrópicas y neuropatía periférica: estado del arte y acuerdo de expertos

Purpose: peripheral neuropathy has a nonspecific and multifactorial clinical spectrum, with frequent underdiagnosis and therapeutics of variable efficacy. There is a heterogeneous prescription of B vitamins, which can play an important role in the management of different neuropathies; however, there are no clinical guidelines in Colombia. The purpose of this work is to guide in the early recognition of peripheral neuropathies and to generate recommendations on the adequate use of neurotropic B vitamins.

Description of the methodology: expert agreement on peripheral neuropathy and the therapeutic role of B vitamins with emphasis on epidemiology in Colombia, diagnosis and treatment.

Contents: in Colombia, the prevalence of peripheral neuropathy is estimated at around 10?%, however, there are no recent data. Among the most frequent etiologies are diabetic neuropathy, infectious, inflammatory, deficiency, toxic and pharmacological. The following screening tools are recommended in the population at risk: DN4, MNSI, monofilament test, vibration test and reflex assessment. Vitamins B1, B6 and B12 are safe, accessible and can be effective in peripheral neuropathy, even when the deficit has not been demonstrated, but with particular requirements in their joint administration.

Conclusions: peripheral neuropathies are a diagnostic and therapeutic challenge that requires timely identification for treatment of the underlying etiology and symptom control. The use of neurotropic B vitamins is effective and safe in peripheral neuropathy deficiency, and also seems to be effective in the management of peripheral neuropathies of different etiologies.