Validation of the Montgomery-Åsberg Depression Rating Scale (MADRS) in Colombia

Juan Fernando Cano, Carlos Gomez Restrepo, Martín Rondón

Research output: Contribution to journalResearch Articlepeer-review

6 Scopus citations

Abstract

Objective To adapt and to validate the Montgomery-Åsberg Depression Rating Scale (MADRS) in Colombia. Methods Observational study for scale validation. Validity criteria were used to determine the severity cut-off points of the tool. Taking into account sensitivity and specificity values, those cut points were contrasted with ICD-10 criteria for depression severity. A a factor analysis was performed. The internal consistencY was determined with the same sample of patients used for the validity criteria. Inter-rater reliability was assessed by evaluating the 22 records of the patients that consented to a video interview. Sensitivity to change was established through a second application of the scale in 28 subjects after a lapse of 14 to 28 days. Results The study was performed in Bogotá, the tool was applied in 150 patients suffering from major depressive disorder. The cut-off point for moderate depression was 20 (sensitivity, 98%; specificity, 96%), and the cut-off point for severe depression was 34 (sensitivity, 98%; specificity, 92%). The tool appears as a unidimensional scale, which possesses a good internal consistency with (α=.9168). The findings of inter-rater reliability evaluation showed the scale as highly reliable (intraclass correlation coefficient=.9833). The instrument has a good sensitivity to change. Conclusions The Colombian version of the Montgomery-Åsberg Depression Rating Scale has good psychometric properties and can be used in clinical practice and in clinical research in the field of depressive disorder.

Translated title of the contributionValidación en Colombia del instrumento para evaluación de la depresión Montgomery-Åsberg Depression Rating Scale (MADRS)
Original languageEnglish (US)
Pages (from-to)146-155
Number of pages10
JournalRevista Colombiana de Psiquiatria
Volume45
Issue number3
DOIs
StatePublished - Jul 1 2016
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

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