Vaccines against Plasmodium vivax: a research challenge.

Manuel A. Patarroyo, Dayana Calderón, Darwin A. Moreno-Pérez

Research output: Contribution to journalReview articlepeer-review

26 Scopus citations

Abstract

Malaria caused by Plasmodium vivax continues being a public health problem in tropical and subtropical areas throughout the whole world. In spite of this species' epidemiological importance, its biological complexity has hampered advances being made in the field of vaccine development. Few antigens have been described and analyzed to date in preclinical and clinical studies, thereby highlighting the great challenge facing groups currently working on this parasite species. This review summarizes the most representative work done during the last few years and discusses the approaches adopted in making progress towards an anti-Plasmodium vivax vaccine.

Original languageEnglish (US)
Pages (from-to)1249-1260
Number of pages12
JournalExpert Review of Vaccines
Volume11
Issue number10
DOIs
StatePublished - Oct 2012

All Science Journal Classification (ASJC) codes

  • Immunology
  • Molecular Medicine
  • Pharmacology
  • Drug Discovery

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