Trypanosoma cruzi I: Towards the need of genetic subdivision?, Part II

Juan David Ramírez, Carolina Hernández

Research output: Contribution to journalArticlepeer-review

17 Scopus citations

Abstract

Chagas disease is a complex zoonosis caused by the kinetoplastid parasite Trypanosoma cruzi. This protozoan exhibits remarkable genetic diversity evinced in at least six Discrete Typing Units (DTUs) with the foreseen emergence of a genotype associated to bats (TcBat). T. cruzi I is the DTU with the broadest geographical distribution and associated to severe cardiomyopathies. In 2011, we published a review questioning the need for genetic subdivision within TcI. However, after six years of intensive research. Herein, we attempted to determine if TcI should be subdivided or not in the light of the current genetic, biological, clinical and ecological data. The future perspectives are discussed.

Original languageEnglish (US)
JournalActa Tropica
DOIs
StateAccepted/In press - Feb 24 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases

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