Toxoplasmosis in South America: a hybridization-driven disease burden?

Lokman Galal; Aurélien Mercier; Hélène Yera; Alejandra de-la-Torre

doi:10.1016/j.pt.2025.10.002

Toxoplasmosis in South America: a hybridization-driven disease burden?

Lokman Galal
, Aurélien Mercier
, Hélène Yera
, Alejandra de-la-Torre

Research output: Contribution to Journal › Short survey › peer-review

4 Scopus citations

Abstract

Human-mediated migrations have reshaped Toxoplasma gondii in South America through massive hybridizations between Old World domestic lineages and wild native populations. We propose that this convergence of domestic adaptation and virulence traits from wild strains underlies the continent's unusually severe disease burden, particularly ocular toxoplasmosis, with major public health implications.

Original language	English (US)
Journal	Trends in Parasitology
DOIs	https://doi.org/10.1016/j.pt.2025.10.002
State	Accepted/In press - 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Parasitology
Infectious Diseases

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10.1016/j.pt.2025.10.002

Cite this

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title = "Toxoplasmosis in South America: a hybridization-driven disease burden?",

abstract = "Human-mediated migrations have reshaped Toxoplasma gondii in South America through massive hybridizations between Old World domestic lineages and wild native populations. We propose that this convergence of domestic adaptation and virulence traits from wild strains underlies the continent's unusually severe disease burden, particularly ocular toxoplasmosis, with major public health implications.",

author = "Lokman Galal and Aur{\'e}lien Mercier and H{\'e}l{\`e}ne Yera and Alejandra de-la-Torre",

note = "Publisher Copyright: {\textcopyright} 2025 Elsevier Ltd",

year = "2025",

doi = "10.1016/j.pt.2025.10.002",

language = "English (US)",

journal = "Trends in Parasitology",

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TY - JOUR

T1 - Toxoplasmosis in South America

T2 - a hybridization-driven disease burden?

AU - Galal, Lokman

AU - Mercier, Aurélien

AU - Yera, Hélène

AU - de-la-Torre, Alejandra

PY - 2025

Y1 - 2025

N2 - Human-mediated migrations have reshaped Toxoplasma gondii in South America through massive hybridizations between Old World domestic lineages and wild native populations. We propose that this convergence of domestic adaptation and virulence traits from wild strains underlies the continent's unusually severe disease burden, particularly ocular toxoplasmosis, with major public health implications.

AB - Human-mediated migrations have reshaped Toxoplasma gondii in South America through massive hybridizations between Old World domestic lineages and wild native populations. We propose that this convergence of domestic adaptation and virulence traits from wild strains underlies the continent's unusually severe disease burden, particularly ocular toxoplasmosis, with major public health implications.

UR - https://www.scopus.com/pages/publications/105019219145

UR - https://www.scopus.com/pages/publications/105019219145#tab=citedBy

U2 - 10.1016/j.pt.2025.10.002

DO - 10.1016/j.pt.2025.10.002

M3 - Short survey

C2 - 41120237

AN - SCOPUS:105019219145

SN - 1471-4922

JO - Trends in Parasitology

JF - Trends in Parasitology

ER -

Toxoplasmosis in South America: a hybridization-driven disease burden?

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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