Abstract
Phenytoin is one of the most widely used antiepileptics because of its great usefulness for different types of seizures and low cost. However, its use is limited by adverse effects, particularly those affecting the central nervous system. This case illustrates a successful pharmacogenetics-based pharmaceutical intervention to optimize phenytoin pharmacotherapy in an intermediate metabolizer patient with clear signs of phenytoin neurotoxicity.
| Translated title of the contribution | Neurological toxicity associated with phenytoin in an intermediate metabolizer patient for CYP2C9 enzyme |
|---|---|
| Original language | Spanish (Colombia) |
| Article number | 3 |
| Pages (from-to) | 228-235 |
| Number of pages | 8 |
| Journal | Pharmaceutical Care Espana |
| Volume | 20 |
| Issue number | 3 |
| State | Published - Jun 15 2018 |
All Science Journal Classification (ASJC) codes
- Pharmacology, Toxicology and Pharmaceutics(all)