Toxicidad neurológica asociada a la fenitoína en un paciente metabolizador intermedio para la enzima CYP2C19

Translated title of the contribution: Neurological toxicity associated with phenytoin in an intermediate metabolizer patient for CYP2C9 enzyme

Research output: Contribution to JournalResearch Articlepeer-review

Abstract

Phenytoin is one of the most widely used antiepileptics because of its great usefulness for different types of seizures and low cost. However, its use is limited by adverse effects, particularly those affecting the central nervous system. This case illustrates a successful pharmacogenetics-based pharmaceutical intervention to optimize phenytoin pharmacotherapy in an intermediate metabolizer patient with clear signs of phenytoin neurotoxicity.
Translated title of the contributionNeurological toxicity associated with phenytoin in an intermediate metabolizer patient for CYP2C9 enzyme
Original languageSpanish (Colombia)
Article number3
Pages (from-to)228-235
Number of pages8
JournalPharmaceutical Care Espana
Volume20
Issue number3
StatePublished - Jun 15 2018

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)

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