Toxicidad neurológica asociada a la fenitoína en un paciente metabolizador intermedio para la enzima CYP2C19: Neurological toxicity associated with phenytoin in an intermediate metabolizer patient for CYP2C9 enzyme

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Phenytoin is one of the most used antiepileptics because of its great utility for
different types of crisis and low cost. However, its use is limited because the adverse
effects, particularly those that affect the central nervous system. This case shows a
successful pharmaceutical intervention based on pharmacogenetics, to optimize
pharmacotherapy with phenytoin in an intermediate metabolizer patient with clear
signs of neurotoxicity for this drug.
Original languageSpanish (Colombia)
Article number3
Pages (from-to)228
Number of pages235
JournalPharmaceutical Care Espana
Issue number3
StatePublished - 2018

All Science Journal Classification (ASJC) codes

  • Pharmacology, Toxicology and Pharmaceutics(all)

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