The nature and nurture of common autoimmunity

John Castiblanco, Juan Manuel Anaya

Research output: Chapter in Book/ReportConference contribution

15 Scopus citations


Autoimmune diseases are a heterogeneous group of disorders where multiple alterations in the immune system result in a spectrum of syndromes that either target specific organs or affect the body systematically. Although their heterogeneity is due to a collection of diverse conditions based on epidemiology, pathology, or diagnostic criteria, the underlying immunogenetic mechanism might be similar. Herein the nature and nurture of autoimmune diseases considered as a trait are reviewed, and a discussion is given on their multifactorial characteristics.

Original languageEnglish (US)
Title of host publicationAutoimmunity, Part A Basic Principles and New Diagnostic Tools
PublisherBlackwell Publishing, Inc.
Number of pages8
ISBN (Print)1573316636, 9781573316637
StatePublished - Aug 2007

Publication series

NameAnnals of the New York Academy of Sciences
ISSN (Print)0077-8923
ISSN (Electronic)1749-6632

All Science Journal Classification (ASJC) codes

  • General Neuroscience
  • General Biochemistry, Genetics and Molecular Biology
  • History and Philosophy of Science


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