The nature and nurture of common autoimmunity

John Castiblanco, Juan-Manuel Anaya

Research output: Contribution to journalArticle

14 Scopus citations


Autoimmune diseases are a heterogeneous group of disorders where multiple alterations in the immune system result in a spectrum of syndromes that either target specific organs or affect the body systematically. Although their heterogeneity is due to a collection of diverse conditions based on epidemiology, pathology, or diagnostic criteria, the underlying immunogenetic mechanism might be similar. Herein the nature and nurture of autoimmune diseases considered as a trait are reviewed, and a discussion is given on their multifactorial characteristics.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalAnnals of the New York Academy of Sciences
StatePublished - Aug 2007


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