Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Laura V. Sánchez, Diana C. Bautista, Andrés F. Corredor, Victor M. Herrera, Luz X. Martinez, Juan Carlos Villar, Juan David Ramírez

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

Original languageEnglish (US)
Pages (from-to)745-748
Number of pages4
JournalMicrobes and Infection
Volume15
Issue number10-11
DOIs
StatePublished - Sep 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients'. Together they form a unique fingerprint.

Cite this