Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Laura V. Sánchez; Diana C. Bautista; Andrés F. Corredor; Victor M. Herrera; Luz X. Martinez; Juan Carlos Villar; Juan David Ramírez

doi:10.1016/j.micinf.2013.06.008

Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Laura V. Sánchez, Diana C. Bautista, Andrés F. Corredor, Victor M. Herrera, Luz X. Martinez, Juan Carlos Villar, Juan David Ramírez

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

Original language	English (US)
Pages (from-to)	745-748
Number of pages	4
Journal	Microbes and Infection
Volume	15
Issue number	10-11
DOIs	https://doi.org/10.1016/j.micinf.2013.06.008
State	Published - Sep 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

Microbiology
Immunology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.micinf.2013.06.008

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title = "Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients",

abstract = "Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.",

author = "S{\'a}nchez, {Laura V.} and Bautista, {Diana C.} and Corredor, {Andr{\'e}s F.} and Herrera, {Victor M.} and Martinez, {Luz X.} and Villar, {Juan Carlos} and Ram{\'i}rez, {Juan David}",

year = "2013",

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language = "English (US)",

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journal = "Microbes and Infection",

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T1 - Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

AU - Sánchez, Laura V.

AU - Bautista, Diana C.

AU - Corredor, Andrés F.

AU - Herrera, Victor M.

AU - Martinez, Luz X.

AU - Villar, Juan Carlos

AU - Ramírez, Juan David

PY - 2013/9

Y1 - 2013/9

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AB - Chagas disease caused by Trypanosoma cruzi is a public health problem in Latin America. This parasite displays a high genetic diversity evidenced in six Discrete Typing Units (DTUs) namely TcI-TcVI. The aim of this study was to observe the temporal variation of the DTUs in asymptomatic patients at three different times (10 days interval). The results showed that intermittence is the rule in the bloodstream of Chagas disease patients. The patients showed different detectable DTUs with short time intervals, which favors the clonal histiotropic model and the multiclonality structure of this parasite.

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JO - Microbes and Infection

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ER -

Temporal variation of Trypanosoma cruzi discrete typing units in asymptomatic Chagas disease patients

Abstract

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UN SDGs

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