Systemic lupus erythematosus in males: A study of 107 Latin American patients

Jose F. Molina; Cristina Drenkard; Javier Molina; Mario H. Cardiel; Oscar Uribe; Juan Manuel Anaya; Luis J. Gomez; Oscar Felipe; Luis A. Ramirez; Donato Alarcon-Segovia

doi:10.1097/00005792-199605000-00002

Systemic lupus erythematosus in males: A study of 107 Latin American patients

Jose F. Molina, Cristina Drenkard, Javier Molina, Mario H. Cardiel, Oscar Uribe, Juan Manuel Anaya, Luis J. Gomez, Oscar Felipe, Luis A. Ramirez, Donato Alarcon-Segovia

Research output: Contribution to journal › Research Article › peer-review

114 Scopus citations

Abstract

Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

Original language	English (US)
Pages (from-to)	124-130
Number of pages	7
Journal	Medicine
Volume	75
Issue number	3
DOIs	https://doi.org/10.1097/00005792-199605000-00002
State	Published - 1996
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Medicine

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10.1097/00005792-199605000-00002

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@article{5e5816c63ef24f05a28dba4f5f9e582a,

title = "Systemic lupus erythematosus in males: A study of 107 Latin American patients",

abstract = "Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.",

author = "Molina, \{Jose F.\} and Cristina Drenkard and Javier Molina and Cardiel, \{Mario H.\} and Oscar Uribe and Anaya, \{Juan Manuel\} and Gomez, \{Luis J.\} and Oscar Felipe and Ramirez, \{Luis A.\} and Donato Alarcon-Segovia",

year = "1996",

doi = "10.1097/00005792-199605000-00002",

language = "English (US)",

volume = "75",

pages = "124--130",

journal = "Medicine",

issn = "0025-7974",

publisher = "Lippincott Williams and Wilkins",

number = "3",

}

TY - JOUR

T1 - Systemic lupus erythematosus in males

T2 - A study of 107 Latin American patients

AU - Molina, Jose F.

AU - Drenkard, Cristina

AU - Molina, Javier

AU - Cardiel, Mario H.

AU - Uribe, Oscar

AU - Anaya, Juan Manuel

AU - Gomez, Luis J.

AU - Felipe, Oscar

AU - Ramirez, Luis A.

AU - Alarcon-Segovia, Donato

PY - 1996

Y1 - 1996

N2 - Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

AB - Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

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U2 - 10.1097/00005792-199605000-00002

DO - 10.1097/00005792-199605000-00002

M3 - Research Article

C2 - 8965681

AN - SCOPUS:19144364191

SN - 0025-7974

VL - 75

SP - 124

EP - 130

JO - Medicine

JF - Medicine

IS - 3

ER -

Systemic lupus erythematosus in males: A study of 107 Latin American patients

Abstract

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