TY - JOUR
T1 - Systemic lupus erythematosus in males
T2 - A study of 107 Latin American patients
AU - Molina, Jose F.
AU - Drenkard, Cristina
AU - Molina, Javier
AU - Cardiel, Mario H.
AU - Uribe, Oscar
AU - Anaya, Juan Manuel
AU - Gomez, Luis J.
AU - Felipe, Oscar
AU - Ramirez, Luis A.
AU - Alarcon-Segovia, Donato
N1 - Copyright:
Copyright 2012 Elsevier B.V., All rights reserved.
PY - 1996
Y1 - 1996
N2 - Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.
AB - Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.
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U2 - 10.1097/00005792-199605000-00002
DO - 10.1097/00005792-199605000-00002
M3 - Article
C2 - 8965681
AN - SCOPUS:19144364191
SN - 0025-7974
VL - 75
SP - 124
EP - 130
JO - Medicine (United States)
JF - Medicine (United States)
IS - 3
ER -