Systemic lupus erythematosus in males: A study of 107 Latin American patients

Jose F. Molina, Cristina Drenkard, Javier Molina, Mario H. Cardiel, Oscar Uribe, Juan Manuel Anaya, Luis J. Gomez, Oscar Felipe, Luis A. Ramirez, Donato Alarcon-Segovia

Research output: Contribution to journalArticlepeer-review

98 Scopus citations

Abstract

Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.

Original languageEnglish (US)
Pages (from-to)124-130
Number of pages7
JournalMedicine
Volume75
Issue number3
DOIs
StatePublished - 1996
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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