Spondyloarthropathies in autoimmune diseases and vice versa

Oscar M. Pérez-Fernández, Rubén D. Mantilla, Paola Cruz-Tapias, Alberto Rodriguez-Rodriguez, Adriana Rojas-Villarraga, Juan Manuel Anaya

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12 Scopus citations


Polyautoimmunity is one of the major clinical characteristics of autoimmune diseases (ADs). The aim of this study was to investigate the prevalence of ADs in spondyloarthropathies (SpAs) and vice versa. This was a two-phase cross-sectional study. First, we examined the presence of ADs in a cohort of patients with SpAs (N = 148). Second, we searched for the presence of SpAs in a well-defined group of patients with ADs (N = 1077) including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), and Sjögren's syndrome (SS). Among patients with SpAs, ankylosing spondylitis was observed in the majority of them (55.6). There were two patients presenting with SS in the SpA group (1.4) and 5 patients with autoimmune thyroiditis (3.5). The global prevalence of ADs in SpAs was 4.86. In the ADs group, there were 5 patients with SpAs (0.46). Our results suggest a lack of association between SpAs and ADs. Accordingly, SpAs might correspond more to autoinflammatory diseases rather than to ADs.

Original languageEnglish (US)
Article number736384
JournalAutoimmune Diseases
Issue number1
StatePublished - 2012

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology
  • Immunology and Microbiology (miscellaneous)


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