Simple proteomic checks for detecting noncoding RNA

Stéphane Cruveiller; Oliver Clay; Kamel Jabbari; Giorgio Bernardi

doi:10.1002/pmic.200600813

Simple proteomic checks for detecting noncoding RNA

Stéphane Cruveiller, Oliver Clay, Kamel Jabbari, Giorgio Bernardi

Research output: Contribution to journal › Research Article › peer-review

6 Scopus citations

Abstract

Proper validation can accelerate sequence-based discovery of proteins and protein-coding genes. Databases currently contain a backlog of experimentally unverified gene models and tentative assignments of observed transcripts to coding or noncoding RNA. We present and apply a general principle, founded on base composition and the genetic code and validated here by bulk 2-D gels, that can improve the reliability of such classifications and of the algorithms or pipelines that lead to them.

Original language	English (US)
Pages (from-to)	361-363
Number of pages	3
Journal	Proteomics
Volume	7
Issue number	3
DOIs	https://doi.org/10.1002/pmic.200600813
State	Published - Feb 2007
Externally published	Yes

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology

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10.1002/pmic.200600813

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AU - Cruveiller, Stéphane

AU - Clay, Oliver

AU - Jabbari, Kamel

AU - Bernardi, Giorgio

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AB - Proper validation can accelerate sequence-based discovery of proteins and protein-coding genes. Databases currently contain a backlog of experimentally unverified gene models and tentative assignments of observed transcripts to coding or noncoding RNA. We present and apply a general principle, founded on base composition and the genetic code and validated here by bulk 2-D gels, that can improve the reliability of such classifications and of the algorithms or pipelines that lead to them.

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DO - 10.1002/pmic.200600813

M3 - Research Article

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JO - Proteomics

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Simple proteomic checks for detecting noncoding RNA

Abstract

All Science Journal Classification (ASJC) codes

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