Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia. VKH syndrome in Colombia

Ligia Alejandra De La Torre Cifuentes, Carol Guayacán, Brahyan Galindo-Mendez

Research output: Contribution to journalArticle

Abstract

Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.
Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data.
Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment.
Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.
Original languageEnglish (US)
Article numberNOII 2016-0391
Pages (from-to)1-13
Number of pages13
JournalOcular Immunology and Inflammation
DOIs
StatePublished - Sep 14 2017

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Uveomeningoencephalitic Syndrome
Colombia
Ophthalmology
Referral and Consultation
Uveitis
Tinnitus
Retinal Detachment
Hearing Loss
Population Groups
Hispanic Americans
Medical Records
Headache
Demography
Recurrence

Cite this

@article{ac5ae82b00204cb38dad7413b3ceec8b,
title = "Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogot{\'a}, Colombia.: VKH syndrome in Colombia",
abstract = "Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95{\%}), 78.3{\%} females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87{\%}), headaches (47.8{\%}), tinnitus (26.1{\%}) and hearing impairments (21.7{\%}). Ophthalmic findings: bilateral serous retinal-detachment (67.4{\%}), non-granulomatous uveitis (52.3{\%}). Most of the patients were diagnosed with probable disease (56.5{\%}). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26{\%} of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.",
author = "{De La Torre Cifuentes}, {Ligia Alejandra} and Carol Guayac{\'a}n and Brahyan Galindo-Mendez",
year = "2017",
month = "9",
day = "14",
doi = "10.1080/09273948.2017.1341536",
language = "English (US)",
pages = "1--13",
journal = "Ocular Immunology and Inflammation",
issn = "0927-3948",
publisher = "Informa Healthcare",

}

TY - JOUR

T1 - Vogt-Koyanagi-Harada Syndrome in a Group of Patients in Two Ophthalmology Referral Centers in Bogotá, Colombia.

T2 - VKH syndrome in Colombia

AU - De La Torre Cifuentes, Ligia Alejandra

AU - Guayacán, Carol

AU - Galindo-Mendez, Brahyan

PY - 2017/9/14

Y1 - 2017/9/14

N2 - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

AB - Purpose: To describe the clinical presentation of Vogt-Koyanagi-Harada syndrome in a group of patients in Colombia.Methods: Retrospective-review of 2638 medical-records of patients with uveitis in two centers during 17 years. Patients with Vogt-Koyanagi-Harada syndrome were gathered to characterize demographic and clinical data. Results: Twenty-five patients with uveitis were diagnosed with Vogt-Koyanagi-Harada syndrome (0.95%), 78.3% females, mean age of diagnosis 37 years old (SD ±29). Twenty-three patients with complete data were included. Main complaints: blurred vision (87%), headaches (47.8%), tinnitus (26.1%) and hearing impairments (21.7%). Ophthalmic findings: bilateral serous retinal-detachment (67.4%), non-granulomatous uveitis (52.3%). Most of the patients were diagnosed with probable disease (56.5%). Mean duration of follow-up was fourteen months; disease relapse was encountered in 26% of patients despite treatment. Conclusion: Patients in Colombia with Vogt-Koyanagi-Harada had clinical features similar to those reported in other Hispanic populations, except for the non-granulomatous uveitis. This disease may be considered as having variation of clinical manifestations across population groups.

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