TY - JOUR
T1 - Repeated genetic adaptation to altitude in two tropical butterflies
AU - Montejo-Kovacevich, Gabriela
AU - Meier, Joana I.
AU - Bacquet, Caroline N.
AU - Warren, Ian A.
AU - Chan, Yingguang Frank
AU - Kucka, Marek
AU - Salazar, Camilo
AU - Rueda-M, Nicol
AU - Montgomery, Stephen H.
AU - McMillan, W. Owen
AU - Kozak, Krzysztof M.
AU - Nadeau, Nicola J.
AU - Martin, Simon H.
AU - Jiggins, Chris D.
N1 - Funding Information:
We are grateful to all the field assistants who have collected samples for this study, Narupa Reserve (Jocotoco Foundation, Ecuador), Jatun Satcha Reserve (Ecuador), and Universidad Regional Amazónica Ikiam for their support. We thank Steven van Belleghem for sharing recombination rates data for H. erato , and Emma Curran and Juan Enciso for providing some of the genomic sequences, and the Butterfly Genetics Lab (Cambridge) for helpful feedback. We thank the McGuire Center for Lepidoptera and Biodiversity, Florida Museum of Natural History, University of Florida, for providing access to their butterfly collection for photographing to C.D.J. (Figs. 2 , 6). G.M.-K. was supported by a Natural Environment Research Council Doctoral Training Partnership (NE/L002507/1). This work, N.J.N. and C.D.J. were supported by the Natural Environment Research Council (grant number: NE/R010331/1) and by a European Research Council Grant (339873) to C.D.J. Some of the sequence data was generated under a NERC fellowship (NE/K008498/1) to N.J.N. Funding was provided to C.N.B. by the Spanish Agency for International Development Cooperation (AECID, grant number 2018SPE0000400194). C.S and N.R. were funded by Fondos Concursables Big - grant IV-FGD005/ IV-FGI006 Universidad del Rosario. SHM was supported by a NERC IRF (NE/N014936/1). Y.F.C. was supported by the European Research Council Starting Grant 639096 “HybridMiX” and the Max Planck Society. Smithsonian Institution Scholarly Studies Award to K.M.K. and W.O.M. Open access funding provided by the University of Cambridge.
Funding Information:
We are grateful to all the field assistants who have collected samples for this study, Narupa Reserve (Jocotoco Foundation, Ecuador), Jatun Satcha Reserve (Ecuador), and Universidad Regional Amazónica Ikiam for their support. We thank Steven van Belleghem for sharing recombination rates data for H. erato, and Emma Curran and Juan Enciso for providing some of the genomic sequences, and the Butterfly Genetics Lab (Cambridge) for helpful feedback. We thank the McGuire Center for Lepidoptera and Biodiversity, Florida Museum of Natural History, University of Florida, for providing access to their butterfly collection for photographing to C.D.J. (Figs. , ). G.M.-K. was supported by a Natural Environment Research Council Doctoral Training Partnership (NE/L002507/1). This work, N.J.N. and C.D.J. were supported by the Natural Environment Research Council (grant number: NE/R010331/1) and by a European Research Council Grant (339873) to C.D.J. Some of the sequence data was generated under a NERC fellowship (NE/K008498/1) to N.J.N. Funding was provided to C.N.B. by the Spanish Agency for International Development Cooperation (AECID, grant number 2018SPE0000400194). C.S and N.R. were funded by Fondos Concursables Big - grant IV-FGD005/ IV-FGI006 Universidad del Rosario. SHM was supported by a NERC IRF (NE/N014936/1). Y.F.C. was supported by the European Research Council Starting Grant 639096 “HybridMiX” and the Max Planck Society. Smithsonian Institution Scholarly Studies Award to K.M.K. and W.O.M. Open access funding provided by the University of Cambridge.
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Repeated evolution can provide insight into the mechanisms that facilitate adaptation to novel or changing environments. Here we study adaptation to altitude in two tropical butterflies, Heliconius erato and H. melpomene, which have repeatedly and independently adapted to montane habitats on either side of the Andes. We sequenced 518 whole genomes from altitudinal transects and found many regions differentiated between highland (~ 1200 m) and lowland (~ 200 m) populations. We show repeated genetic differentiation across replicate populations within species, including allopatric comparisons. In contrast, there is little molecular parallelism between the two species. By sampling five close relatives, we find that a large proportion of divergent regions identified within species have arisen from standing variation and putative adaptive introgression from high-altitude specialist species. Taken together our study supports a role for both standing genetic variation and gene flow from independently adapted species in promoting parallel local adaptation to the environment.
AB - Repeated evolution can provide insight into the mechanisms that facilitate adaptation to novel or changing environments. Here we study adaptation to altitude in two tropical butterflies, Heliconius erato and H. melpomene, which have repeatedly and independently adapted to montane habitats on either side of the Andes. We sequenced 518 whole genomes from altitudinal transects and found many regions differentiated between highland (~ 1200 m) and lowland (~ 200 m) populations. We show repeated genetic differentiation across replicate populations within species, including allopatric comparisons. In contrast, there is little molecular parallelism between the two species. By sampling five close relatives, we find that a large proportion of divergent regions identified within species have arisen from standing variation and putative adaptive introgression from high-altitude specialist species. Taken together our study supports a role for both standing genetic variation and gene flow from independently adapted species in promoting parallel local adaptation to the environment.
UR - https://www.scopus.com/pages/publications/85135729302
UR - https://www.scopus.com/inward/citedby.url?scp=85135729302&partnerID=8YFLogxK
U2 - 10.1038/s41467-022-32316-x
DO - 10.1038/s41467-022-32316-x
M3 - Research Article
C2 - 35945236
AN - SCOPUS:85135729302
SN - 2041-1723
VL - 13
JO - Nature Communications
JF - Nature Communications
M1 - 4676
ER -
