Relation between EEG activity and brain oxygenation in preterm neonates

Alexander Caicedo, Liesbeth Thewissen, Anne Smits, Gunnar Naulaers, Karel Allegaert, Sabine Van Huffel

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


This study investigates the relationship between brain oxygenation, assessed by means of near infrared spectroscopy (NIRS), and brain function, assessed by means of electroencephalography (EEG). Using NIRS signals measuring the regional cerebral oxygen saturation (rScO2) and computing the fractional tissue oxygen extraction (FTOE), we compared how these variables relate to different features extracted from the EEG, such as the inter-burst interval (IBI) duration and amplitude, the amplitude of the EEG, and the amplitude of the burst. A cohort of 22 neonates undergoing sedation by propofol was studied and a regression of the NIRS-derived values to the different EEG features was made. We found that higher values of FTOE were related to higher values of EEG amplitude. These results might be of used in the monitoring of proper brain function in neonates.

Original languageEnglish (US)
Pages (from-to)133-139
Number of pages7
JournalAdvances in Experimental Medicine and Biology
StatePublished - Jan 1 2017
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology


Dive into the research topics of 'Relation between EEG activity and brain oxygenation in preterm neonates'. Together they form a unique fingerprint.

Cite this