Abstract
Congenital toxoplasmosis is suspected when seroconversion occurs in a pregnant woman, and it
is confirmed by one or more biologic tests (polymerase chain reaction on amniotic fluid or
neonatal serodiagnosis). The methods used are diagnostic in more than 95% of cases at birth and in
100% of cases by the age of 9 months.1 Ocular lesions represent the most frequent complication of
congenital toxoplasmosis, independent of any treatment.2 The risk of toxoplasmic retinochoroiditis
is highly unpredictable, however, mainly because the pathophysiology is poorly understood.3 By
school age, 10% to 20% of children with congenital toxoplasmosis have one or more retinochoroidal
lesions, but more than 90% of them have normal vision in both eyes; bilateral blindness is very
rare.4–6 This article focuses on the controversy surrounding the effectiveness of screening and
treatment for children with congenital toxoplasmosis.
is confirmed by one or more biologic tests (polymerase chain reaction on amniotic fluid or
neonatal serodiagnosis). The methods used are diagnostic in more than 95% of cases at birth and in
100% of cases by the age of 9 months.1 Ocular lesions represent the most frequent complication of
congenital toxoplasmosis, independent of any treatment.2 The risk of toxoplasmic retinochoroiditis
is highly unpredictable, however, mainly because the pathophysiology is poorly understood.3 By
school age, 10% to 20% of children with congenital toxoplasmosis have one or more retinochoroidal
lesions, but more than 90% of them have normal vision in both eyes; bilateral blindness is very
rare.4–6 This article focuses on the controversy surrounding the effectiveness of screening and
treatment for children with congenital toxoplasmosis.
| Translated title of the contribution | Prevención de Retinochoroiditis en Toxoplasmosis Congénita Europa Versus América del Sur |
|---|---|
| Original language | English |
| Pages (from-to) | 601-603 |
| Number of pages | 3 |
| Journal | Pediatric Infectious Disease Journal |
| Volume | 30 |
| Issue number | 7 |
| State | Published - Jul 2011 |