Personalized medicine. Closing the gap between knowledge and clinical practice

Juan Manuel Anaya, Carolina Duarte-Rey, Juan C. Sarmiento-Monroy, David Bardey, John Castiblanco, Adriana Rojas-Villarraga

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations

Abstract

Personalized medicine encompasses a broad and evolving field informed by a patient distinctive information and biomarker profile. Although terminology is evolving and some semantic interpretations exist (e.g., personalized, individualized, precision), in a broad sense personalized medicine can be coined as: “To practice medicine as it once used to be in the past using the current biotechnological tools.” A humanized approach to personalized medicine would offer the possibility of exploiting systems biology and its concept of P5 medicine, where predictive factors for developing a disease should be examined within populations in order to establish preventive measures on at-risk individuals, for whom healthcare should be personalized and participatory. Herein, the process of personalized medicine is presented together with the options that can be offered in health care systems with limited resources for diseases like rheumatoid arthritis and type 1 diabetes.

Original languageEnglish (US)
Pages (from-to)833-842
Number of pages10
JournalAutoimmunity Reviews
Volume15
Issue number8
DOIs
StatePublished - Aug 1 2016

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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