Abstract
Thrombotic microangiopathies (TMA) include a variety of vascular disorders characterized by
the presence of microthrombi, coagulopathy by platelet activation and consumption, and systemic damage. The most frequent secondary causes are infections and some medications.
However, the presence of chemotherapeutic agents is not so common, and the induction of
TMA by oxaliplatin is poorly understood, with few published case reports. We present the case
of a patient with a history of gallbladder carcinoma, in whom findings compatible with TMA
were documented, and with a temporal and sole relation to oxaliplatin.
the presence of microthrombi, coagulopathy by platelet activation and consumption, and systemic damage. The most frequent secondary causes are infections and some medications.
However, the presence of chemotherapeutic agents is not so common, and the induction of
TMA by oxaliplatin is poorly understood, with few published case reports. We present the case
of a patient with a history of gallbladder carcinoma, in whom findings compatible with TMA
were documented, and with a temporal and sole relation to oxaliplatin.
| Translated title of the contribution | MIcroangiopatia trombotica inducida por oxaliplatino, en un paciente con carcinoma de vesícula estadio IV. ¿causal directo o multifactorial? |
|---|---|
| Original language | English (US) |
| Pages (from-to) | 1191 |
| Number of pages | 1195 |
| Journal | Case Reports in Oncology |
| Volume | 13 |
| State | Published - Sep 29 2020 |
| Externally published | Yes |