Mecanobiología de reparación del ligamento

Translated title of the contribution: Mechanobiology of ligament repair

Rosy Paola Cárdenas Sandoval, Diego Alexander Garzón Alvarado, Liliana Mabel Peinado Cortés

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations


After a lengthy period of recovery, approximately a year, the healed ligament neither achieve the mechanical properties nor qualities of a normal ligament becoming a tissue liable to chronic sprains. This fact is associated with a low production of collagen and to the new random direction of fibers, which leads to an abnormal distribution of stresses. Nowadays, it is accepted that mechanical load has beneficial effects on the tissue repair, to stimulate the cellular proliferation and the collagen production. Thus, to understand how the repairing tissue answers to mechanical stimuli, it is necessary to resort to mechanobiology, an approach describing the mechanotransduction in tissue. Thus, the aim of present paper is to provide a review on the mechanobiology and the factors influencing in repair process of ligament after a lesion.

Translated title of the contributionMechanobiology of ligament repair
Original languageSpanish
Pages (from-to)155-169
Number of pages15
JournalRevista Cubana de Investigaciones Biomedicas
Issue number1
StatePublished - Jan 2010
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Medicine


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