Abstract
Introduction. An estimated 4.2 million deaths occur annually in the first 30 postoperative days. The Lancet Commission on Global Surgery highlights the importance of measuring and reducing this mortality. This study developed a perioperative mortality calculator specific to the Colombian population, aiming to identify and intervene early in patients at high risk.
Methods. We used data from the multicenter ColSOS study, which included 3807 patients from 54 centers in Colombia. Clinical, sociodemographic and perioperative variables were collected; missing data were handled with multiple imputation. Variables were selected by bivariate analysis, Lasso regression and Recursive Feature Elimination (RFE). Predictive models were compared using logistic regression and XGBoost, evaluating their performance with cross-validation.
Results. The XGBoost model was selected because it showed better sensitivity and fewer false negatives than logistic regression. The importance in predicting ASA classification, chronic obstructive pulmonary disease, hemodynamic instability and urgency of the procedure was highlighted. The model predicted mortality with an area under the curve (AUC) of 0.87.
Conclusion. The present study has developed the first perioperative mortality calculator designed for the Colombian population, including multiple surgical specialties. The selected machine learning model presents a sensitivity and specificity that make it comparable to the best international tools. The implementation of this tool allows early identification and management of patients at risk, which could improve surgical care in Colombia.
Methods. We used data from the multicenter ColSOS study, which included 3807 patients from 54 centers in Colombia. Clinical, sociodemographic and perioperative variables were collected; missing data were handled with multiple imputation. Variables were selected by bivariate analysis, Lasso regression and Recursive Feature Elimination (RFE). Predictive models were compared using logistic regression and XGBoost, evaluating their performance with cross-validation.
Results. The XGBoost model was selected because it showed better sensitivity and fewer false negatives than logistic regression. The importance in predicting ASA classification, chronic obstructive pulmonary disease, hemodynamic instability and urgency of the procedure was highlighted. The model predicted mortality with an area under the curve (AUC) of 0.87.
Conclusion. The present study has developed the first perioperative mortality calculator designed for the Colombian population, including multiple surgical specialties. The selected machine learning model presents a sensitivity and specificity that make it comparable to the best international tools. The implementation of this tool allows early identification and management of patients at risk, which could improve surgical care in Colombia.
| Translated title of the contribution | Artificial Intelligence in Surgery: Development and validation of a Colombian perioperative mortality risk calculator |
|---|---|
| Original language | Spanish (Colombia) |
| Pages (from-to) | 474-485 |
| Number of pages | 12 |
| Journal | Revista Colombiana de Cirugia |
| DOIs | |
| State | Published - Nov 8 2024 |
All Science Journal Classification (ASJC) codes
- Public Health, Environmental and Occupational Health
- Epidemiology
- Health Informatics
- Surgery
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Trabajo ganador del Tercer puesto en el Concurso Nacional de Investigación en Cirugía “José Félix Patiño Restrepo”, categoría Médicos Residentes, Asociación Colombiana de Cirugía,
Lozano-Suárez, N. (Recipient), Pérez-Rivera, C. J. (Recipient) & Briceno Ayala, L. (Recipient), Aug 9 2024
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