HLA Association with Autoimmune Diseases

Juan-Manuel Anaya

Research output: Chapter in Book/ReportChapter (peer-reviewed)peer-review


Autoimmune diseases (ADs) are chronic complex inflammatory diseases. They are considered to be either specific or systemic and characterized by inducing immune humoral (B cell) or cell (T cells) responses. Although their etiology is unknown, they are well known to have environmental and polygenic components that are involved in defining susceptibility or protection. Thus, the sum of the genes involved in ADs makes up the genetic component that defines them. ADs are presented with a multifactorial genetic inheritance pattern which does not completely follow a classical Mendelian model.
Original languageEnglish
Title of host publicationAutoimmunity. From Bench to Bedside
PublisherUniversidad del Rosario
Pages271 - 285
ISBN (Print)978-958-738-366-9
StatePublished - Oct 10 2013


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