TY - JOUR
T1 - High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia
AU - Hernández, Carolina
AU - Vera, Mauricio Javier
AU - Cucunubá, Zulma
AU - Flórez, Carolina
AU - Cantillo, Omar
AU - Buitrago, Luz Stella
AU - González, Marina Stella
AU - Ardila, Susanne
AU - Dueñas, Liliana Zuleta
AU - Tovar, Rubn
AU - Forero, Luis Fernando
AU - Ramírez, Juan David
N1 - Publisher Copyright:
© 2016 The Author.
PY - 2016/10/15
Y1 - 2016/10/15
N2 - Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.
AB - Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.
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U2 - 10.1093/infdis/jiw360
DO - 10.1093/infdis/jiw360
M3 - Article
C2 - 27511897
AN - SCOPUS:84990982199
SN - 0022-1899
VL - 214
SP - 1252
EP - 1255
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 8
ER -
