High-Resolution Molecular Typing of Trypanosoma cruzi in 2 Large Outbreaks of Acute Chagas Disease in Colombia

Carolina Hernández, Mauricio Javier Vera, Zulma Cucunubá, Carolina Flórez, Omar Cantillo, Luz Stella Buitrago, Marina Stella González, Susanne Ardila, Liliana Zuleta Dueñas, Rubn Tovar, Luis Fernando Forero, Juan David Ramírez

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Oral transmission of Trypanosoma cruzi has gained relevance because of its association with high morbidity and lethality rates. This transmission route is responsible for maintaining the infection of the parasite in sylvatic cycles, and human cases have been associated mainly with the consumption of food contaminated with triatomine feces or didelphid secretions. Several ecological changes allow the intrusion of sylvatic reservoirs and triatomines to the domestic environments with subsequent food contamination. Here, high-resolution molecular tools were used to detect and genotype T. cruzi across humans, reservoirs, and insect vectors in 2 acute outbreaks of presumptive oral transmission in eastern Colombia.

Original languageEnglish (US)
Pages (from-to)1252-1255
Number of pages4
JournalJournal of Infectious Diseases
Volume214
Issue number8
DOIs
StatePublished - Oct 15 2016

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Infectious Diseases

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