Genetic restriction in two conserved regions of Plasmodium falciparum EBA 175.

Manuel Alfonso Patarroyo, Edward Carrillo, Luis Murillo

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The 175 kDa erythrocyte binding antigen
lEBA-175), first reported by Camus and David
[1], is a Plasmodium falciparum specific protein
involved in the primary merozoite-erythrocyte
interaction. It shares the general primary structure
pattern and general intron-exon organization
characterizing other proteins involved in the
target cell recognition by malarial parasites such
as the Duffy receptor of P. vivax and P. knowlesi,
the reticulocyte binding protein of P. vivax and
the apical merozoite antigen 1 of P. fidciparum
This fact raised the hypotheses for their consideration as a protein family
Original languageEnglish (US)
Pages (from-to)255 - 258
JournalMolecular and Biochemical Parasitology
Volume1
Issue number87
StatePublished - 1997

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