Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

Translated title of the contribution: Functionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population

Juan F Cano, Julián Ortegón-Valencia, Carlos Pedraza-Perez, Rodrigo Córdoba-Rojas, Ana Olarte-Armenta, Alexie Vallejo-Silva, Jairo González-Díaz

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: There is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. Methods: Naturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. Results: Patients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. Conclusions: The results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.

Translated title of the contributionFunctionality During the First Five Years After the Diagnosis of Schizophrenia. A Cohort Study in a Colombian Population
Original languageEnglish
JournalRevista Colombiana de Psiquiatria
Early online dateJan 4 2021
DOIs
StateE-pub ahead of print - Jan 4 2021

All Science Journal Classification (ASJC) codes

  • Psychiatry and Mental health

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