TY - JOUR
T1 - Funcionalidad en los primeros cinco años después del diagnóstico de esquizofrenia. Estudio de cohorte en población colombiana
AU - Cano, Juan F.
AU - Ortegón-Valencia, Julián
AU - Pedraza-Perez, Carlos
AU - Córdoba-Rojas, Rodrigo
AU - Olarte-Armenta, Ana
AU - Vallejo-Silva, Alexie
AU - González-Díaz, Jairo
N1 - Funding Information:
This research was partly supported by an unrestrictive grant from Janssen-Cilag.
Publisher Copyright:
© 2020 Asociación Colombiana de Psiquiatría
Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2021
Y1 - 2021
N2 - Objective: There is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. Methods: Naturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. Results: Patients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. Conclusions: The results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.
AB - Objective: There is a lack of studies on the natural history of the initial stages of schizophrenia in Colombia. This study aims to assess functionality in the first five years after the diagnosis of schizophrenia. Methods: Naturalistic longitudinal study of 50 patients with early schizophrenia evaluated between 2011 and 2014. Data about demographic background, symptoms, introspection, treatment and adverse reactions were collected in all patients every 3 months for at least 3-5 years. Functionality was measured with the Global Assessment of Functioning (GAF) and Personal and Social Performance (PSP) scales. Results: Patients were followed up for a mean of 174 ± 62.5 weeks and showed moderate difficulties in overall functioning. This functioning was modified by polypharmacy, degree of introspection, changes in antipsychotic regimens, and the number of episodes, relapses and hospitalisations. Conclusions: The results suggest that functional outcomes seem to be related to the use of polypharmacy, degree of insight, changes in antipsychotic regimens, and number of episodes, relapses and hospitalisations during the first years of schizophrenia.
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U2 - 10.1016/j.rcp.2020.11.005
DO - 10.1016/j.rcp.2020.11.005
M3 - Artículo
AN - SCOPUS:85098871936
JO - Revista Colombiana de Psiquiatria
JF - Revista Colombiana de Psiquiatria
SN - 0034-7450
ER -