Epidemiology of sepsis in Colombian intensive care units

Guillermo Ortíz, Carmelo Dueñas, Ferney Rodríguez, Lena Barrera, Gisela de La Rosa, Rodolfo Dennis, Marcela Granados, Darío Londoño, Francisco Molina, Fabián Jaimes

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

Introduction: Currently, there is not enough data available concerning sepsis in developing countries, especially in Latin America. Objective: We developed a study aimed at determining the frequency, clinical and epidemiological characteristics, and the consequences of sepsis in patients requiring admission to intensive care units in Colombia. Materials and methods: This was a secondary analysis of a prospective cohort study carried out over a six-month period, from September 1, 2007, to February 28, 2008, in ten medical/surgical intensive care units in four Colombian cities. Patients were considered eligible if they had a probable or confirmed diagnosis of infection according to medical records. We recorded demographic characteristics, first admission diagnosis and co-morbidities, clinical status, and sepsis, severe sepsis or septic shock. Results: During the study period, 826 patients were admitted to the intensive care units. From these patients, 421 (51%) developed sepsis in the community, 361 (44%) in the ICU, and 44 (5%) during hospitalization in the general ward. Two hundred and fifty three patients (30.6%) had involvement of one organ system: 20% had respiratory involvement, followed by kidney and central nervous system involvement with 3.4% and 2.7%, respectively. Conclusions: In our cohort of septic patients, the prevalence of sepsis treated in ICU is similar to that reported in other studies, as well as the overall mortality.

Original languageEnglish (US)
Pages (from-to)40-47
Number of pages8
JournalBiomedica
Volume34
Issue number1
DOIs
StatePublished - 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology

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