Introduction: Several risk factors affect endothelial function, which is the first step in the genesis of cardiovascular disease (CVD). The non-invasive evaluation of endothelial function, through the measurement of flow-mediated vasodilatation (FMV) and pulse wave velocity (PWR), represent useful tools in estimating the risk of LCA, as it is a simple, accessible, reliable and reproducible methodology. Objective: To determine endothelial function and evaluate its relationship with risk factors associated with CVD in sedentary adults. Methods: Descriptive and cross-sectional study in 14 subjects (age 30.7±7.9 years, weight 71.5±12.9 kg, BMI 26.2±3.4 kg/m2) of both sexes, without documented cardiovascular disease. Measures of aerobic capacity, muscle strength, body composition, lipid profile and fasting glucose were obtained. Atherogenic ratios were calculated: cholesterol/c-HDL, c-LDL/c-HDL, triglycerides/c-HDL, lipid-metabolic index (ILM) and LCA score. Endothelial function was studied with the flow-mediated vasodilatation test (FMV) and pulse wave velocity (PFOV). Results: After adjusting for age and weight, subjects with a higher value of MFV showed an inverse relationship with PFV (r = - 0.648; p<0.01). Improved aerobic and muscle performance was inversely related to fasting glucose levels (r = -0.603, p<0.05) and percentage of body fat (r = -0.547, p<0.05), respectively. Conclusion: In sedentary adults, endothelial function and physical fitness are associated with improved cardiovascular health. Early detection of cardiovascular risk will allow appropriate therapeutic measures to be taken to prevent or at least delay future complications of the disease. Larger studies are needed to verify the findings found in this paper.
|Translated title of the contribution||Endothelial function and cardiovascular risk factors in sedentary adults|
|Number of pages||1|
|Journal||Revista Brasileira De Ciência & Movimento|
|State||Published - 2015|