Effects of Moringa oleifera on Glycaemia and Insulin Levels: A Review of Animal and Human Studies

Karina Vargas-Sánchez, Edwin Garay-Jaramillo, Rodrigo Esteban Gonzalez Reyes

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations


Diabetes and related neurological complications are serious worldwide public health problems. The increasing number of affected individuals make it necessary to implement novel nutritional and therapeutic interventions. The tree Moringa oleifera (MO) has been used as a food source and for traditional medicine purposes due to possible antihyperglycemic, antioxidant, anti-inflammatory, and lipid regulating properties. These properties may be explained by the presence of numerous phytochemicals in the leaves, fruits, roots and, oil of the tree. The evidence for acute antihyperglycemic effects of MO extract on diabetic animal models seems to be robust, but more chronic and long-term studies are needed. In contrast, the hypoglycemic effects of MO on humans are not as clear. The scarce number of human studies, together with a diverse range of methodologies and MO doses, may explain this. In addition, evidence regarding changes in insulin levels due to MO intervention is ambiguous, both in animal and human studies. Therefore, more structured studies are needed to clarify if MO has an effect on insulin levels or activity
Translated title of the contributionUna revisión de los efectos metabólicos y sobre el sistema nervioso de Moringa oleifera
Original languageEnglish (US)
Article number2907
Pages (from-to)1-19
Number of pages19
Issue number12
StatePublished - Dec 2 2019


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