TY - JOUR
T1 - Effectiveness of physical exercise on fatigue in cancer patients during active treatment: A systematic review and meta-analysis
AU - Meneses-Echávez, Jose Francisco
AU - González-Jiménez, Emilio
AU - Correa-Bautista, Jorge Enrique
AU - Valle, Jacqueline Schmidt Río
AU - Ramírez-Vélez, Robinson
PY - 2015/1/1
Y1 - 2015/1/1
N2 - © 2015, Fundacao Oswaldo Cruz. All rights reserved.This study aimed to determine the effectiveness of physical exercise in decreasing fatigue in cancer patients during active treatment. The PubMed Central, EMBASE, and OVID databases were consulted up to April 2014 to identify randomized clinical trials that evaluated the effect of exercise on fatigue in cancer patients undergoing active treatment. Eleven studies (n = 1,407) were included. Chemotherapy was the most common form of treatment (n = 1,028). The studies showed a low risk of bias and high methodological quality. Effect estimates showed that physical exercise significantly improved fatigue (SMD = -3.0; 95%CI: -5.21; -0.80), p <0.0001. Similar effects were found for resistance training (SMD = -4.5; 95%CI: -7.24; -1.82), p = 0.001. Significant improvements were found in breast and prostate cancer patients (p <0.05). Exercise is a safe and effective intervention in the management fatigue in cancer patients undergoing active treatment.
AB - © 2015, Fundacao Oswaldo Cruz. All rights reserved.This study aimed to determine the effectiveness of physical exercise in decreasing fatigue in cancer patients during active treatment. The PubMed Central, EMBASE, and OVID databases were consulted up to April 2014 to identify randomized clinical trials that evaluated the effect of exercise on fatigue in cancer patients undergoing active treatment. Eleven studies (n = 1,407) were included. Chemotherapy was the most common form of treatment (n = 1,028). The studies showed a low risk of bias and high methodological quality. Effect estimates showed that physical exercise significantly improved fatigue (SMD = -3.0; 95%CI: -5.21; -0.80), p <0.0001. Similar effects were found for resistance training (SMD = -4.5; 95%CI: -7.24; -1.82), p = 0.001. Significant improvements were found in breast and prostate cancer patients (p <0.05). Exercise is a safe and effective intervention in the management fatigue in cancer patients undergoing active treatment.
U2 - 10.1590/0102-311X00114414
DO - 10.1590/0102-311X00114414
M3 - Literature review
SN - 0102-311X
SP - 667
EP - 681
JO - Cadernos de Saude Publica
JF - Cadernos de Saude Publica
ER -
