Drug reaction with eosinophilia and systemic symptoms due to carbamazepine. Pediatric case

Rocío del P. Pereira-Ospina; Ana M. Bejarano-Quintero; José M. Suescún-Vargas; Javier Y. Pinzón-Salamanca

doi:10.5546/aap.2018.e433

Drug reaction with eosinophilia and systemic symptoms due to carbamazepine. Pediatric case

Translated title of the contribution: Drug reaction with eosinophilia and systemic symptoms due to carbamazepine. Pediatric case

Rocío del P. Pereira-Ospina, Ana M. Bejarano-Quintero, José M. Suescún-Vargas, Javier Y. Pinzón-Salamanca

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Severe skin reactions include Stevens-Johnson Syndrome, toxic epidermal necrolysis and Drug reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome, which are uncommon in the pediatric population (incidence 1/1000-10 000 children), but they have bad prognosis. Drug-sensitive Syndrome with eosinophilia and systemic symptoms consists in rash, hematological abnormalities, lymphadenopathy and organ involvement. We report the case of a 12-year-old male patient who developed this pathology after initiating anticonvulsant therapy with carbamazepine. We consider that it is important to be aware of this disease and to include it among the differential diagnoses in patients with similar conditions because this syndrome is life-threatening.

Translated title of the contribution	Drug reaction with eosinophilia and systemic symptoms due to carbamazepine. Pediatric case
Original language	Spanish
Pages (from-to)	e433-e436
Journal	Archivos Argentinos de Pediatria
Volume	116
Issue number	3
DOIs	https://doi.org/10.5546/aap.2018.e433
State	Published - Jun 2018

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health

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10.5546/aap.2018.e433

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abstract = "Severe skin reactions include Stevens-Johnson Syndrome, toxicepidermal necrolysis and Drug reaction with Eosinophiliaand Systemic Symptoms (DRESS) syndrome, which areuncommon in the pediatric population (incidence 1/1000-10000 children), but they have bad prognosis. Drug-sensitiveSyndrome with eosinophilia and systemic symptoms consistsin rash, hematological abnormalities, lymphadenopathy andorgan involvement.We report the case of a 12-year-old male patient who developedthis pathology after initiating anticonvulsant therapy withcarbamazepine. We consider that it is important to be aware ofthis disease and to include it among the differential diagnosesin patients with similar conditions because this syndrome islife-threatening",

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AU - Pereira-Ospina, Rocío del P.

AU - Bejarano-Quintero, Ana M.

AU - Suescún-Vargas, José M.

AU - Pinzón-Salamanca, Javier Y.

PY - 2018/6

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AB - Severe skin reactions include Stevens-Johnson Syndrome, toxicepidermal necrolysis and Drug reaction with Eosinophiliaand Systemic Symptoms (DRESS) syndrome, which areuncommon in the pediatric population (incidence 1/1000-10000 children), but they have bad prognosis. Drug-sensitiveSyndrome with eosinophilia and systemic symptoms consistsin rash, hematological abnormalities, lymphadenopathy andorgan involvement.We report the case of a 12-year-old male patient who developedthis pathology after initiating anticonvulsant therapy withcarbamazepine. We consider that it is important to be aware ofthis disease and to include it among the differential diagnosesin patients with similar conditions because this syndrome islife-threatening

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Drug reaction with eosinophilia and systemic symptoms due to carbamazepine. Pediatric case

Abstract

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